Pump Serum is one of the most comprehensive nitric oxide pre workouts.
With 31 grams of high quality compounds, these ingredients are well rounded for maximizing vasodilation and pumps.
The pumps will last for hours, easily.
From increasing water retention in muscles to increasing blood flow, there's not a single component missing.
This is formulated to stimulate pumps from every angle possible.
Use discount code FITFREK.
Huge Nutrition, or Huge Supplements, are known for their hardcore potent supplements.
Since they've surfaced, they've been making fully transparent and dosed formulas.
One of those supplements is Pump Serum.
Although this is the second version, the first one was already great.
However v2 takes things to the next level.
It has a full dose of pure citrulline, glycerpump, Nitrosingine and much more.
The scoops are huge, nearly the size of protein servings.
Originally, Pump Serum had a formula that was intense.
Things have been taken up a notch and the second version has one of the best pump formulas we've seen to date.
The second version of Pump Serum contains over 20g of nitric oxide boosters and 2g of strong nootropics.
In fact, the latest version made our top list for nitric oxide boosters.
Here's my video review using Pump Serum.
The improvements are not subtle and all together, makes a huge difference in the gym.
It's price tag is the same, but there are added ingredients at generous dosages.
Each serving packs 8g of citrulline, NitroSigine and even GlycerPump.
It's rare to find 8g citrulline, let alone the other patented ingredients in here that make it a very strong nitric oxide booster.
There's also agmatine, beet root and pomegranate extract.
And Pump Serum isn't just for pumps.
With 3g betaine anhydrous, you're getting a full dose for strength and power.
We'll dig into the ingredients...
It's hard to believe this.
But you know things are getting serious when HugeSupplements starts with a big 8 grams of l-citrulline.
The previous version of Pump Serum didn't even have citrulline, but it looks like if they're going to have it, they'll it properly.
There's a huge difference between 10 grams of citrulline vs 5 grams.
And here there's 8 grams, but it's closer to the 10 gram scale.
Citrulline will increase l-arginine in the blood, which will help increase vasodilation.
Vasodilation is where the blood vessels relax and widens, helping blood flow.
This will help reduce blood pressure, improve nutrient delivery and ultimately result in great pumps.
Arginine on it's own is not as effective as citrulline because it breaks down too easily in the digestive process. 
Citrulline converts to arginine in the kidneys,  and the digestive system won't interfere with citrulline's ability to increase vasodilation.
Increased vasodilation doesn't just mean better pumps.
It also means it'll help remove metabolic waste removal, reducing soreness and fatigue.
Betaine is often used in pre workouts for it's osmotic hydration properties.
This ingredient is well used across the supplements from HugeSupplements.
From their Wrecked pre workout, to their intra, Formula XII and now their nitric oxide booster.
Betaine is a osmolyte methyl donor  that helps with performance in the gym [4, 5, 6], muscle building [7, 8], cardiovascular health [4, 9, 10], fat loss [11, 12] and even protects cells against heat shock [4, 13].
It's mostly here for it's hyperhydration benefits as it's an osmolyte.
It increases water flow into cells, helping that pump effect that is different from the traditional nitric oxide booster.
In studies, this is dosed at 2.5g and there's even more cell hydration benefits that'll come from glycerol below.
The next ingredient is GlycerPump, another hyperhydrating ingredient that's a osmotic agent.
It works even better than betaine when it comes to drawing more water into muscles.
GlycerPump uses 65% glycerol, which is also known as glycerin.
Glycerol is a sugar alcohol that's hydrogen bonds with water, which can draw more into muscles.
Increasing the water volume in muscle tissue and cells will help create an incredible cellular hydration effect.
Although this is here mostly for it's ability to draw more water into muscle, it also has benefits for endurance.
Studies have found consuming glycerol can improve endurance.
Trained athletes can last 21% longer than placebo when it comes to cycling to exhaustion. 
And they were able to do this while reducing their heart rates. 
Further studies found athletes who consumed glycerol, water and carbohydrates lasted 23% longer than the group that used just water and carbohydrates. 
Combined with betaine anhydrous, this should create an incredible synergy for increased blood flow and long lasting pumps, not to mention the performance boost from both of these ingredients.
Beet root extract is full of nitrates and metabolites that are full of benefits.
The nitrates in beetroot will reduce blood pressure and decrease the risk of cardiovascular diseases in healthy adults. 
There's plenty of evidence that beetroot can treat hypertension. 
Researchers also found beetroot to increase endurance and reduce fatigue, in both anaerobic and aerobic exercises. 
While the blood pressure reducing effects are great, beetroot is mainly used here to increase vasodilation.
This ingredient combined with the other ingredients that's included Pump Serum will result in some nasty and amazing pumps.
Focus and motivation is what tyrosine is good at.
The reason for this is because it's the precursor for the feel good neurotransmitters such as dopamine and norepinephrine. 
It works well with caffeine, however here it's used without any stimulants.
Studies have shown it is very useful when you're sleep deprived or under stress. 
We've already covered how L-citrulline is far superior than L-arginine.
Nutrition21 overcame some obstacles when it came to arginine by using inositol stabilized arginine silicate. 
Researches shows it's effectiveness with 1.5g doses including better bioavailability over plain L-arginine, N.O. enhancements and even some mental function improvements.
Because of it's stabilized composition, it works better than L-arginine and works for 6 hours. [20, 21]
Nitrosigine decreases the enzyme of arginase which can break down arginine. 
Citrulline can also do this so using both has a double punch combo against arginase. 
Nitrosigine has nitric oxide benefits that's comparable to 8 grams of citrulline malate from a 1.5 gram dose. 
And like citrulline, it can reduce muscle damage and inflammation, resulting in less soreness and faster recovery.
We've already covered citrulline, Nitrosigine and now we're on the next best pump ingredient.
Citrulline and Nitrosigine can increase arginine levels in the blood, but agmatine has the ability to prevent the nitric oxide levels from decreasing.
Agmatine is a metabolite of arginine, which works as a arginase inhibitor. 
Preventing the breakdown of arginase means more nitric oxide, resulting in more and longer lasting pumps.
Agmatine's specialist is defensive, it defends nitric oxide levels from decreasing.
Additionally, agmatine can increase N.O. levels by stimulating synthase production. 
And because agmatine can work as a neurotransmitter, it has a uplift effect on mood. 
Pump Serum is a well rounded nitric oxide booster, and because of agmatine, those improved levels will stay elevated while giving a boost to mood.
With a full 1,250mg dose, you're going to get way more than what most pump formula's offer as you're already getting citrulline, NitroSigine and more.
And if you stack this with Wrecked, you'll be getting more agmatine, in addition to more pumps thanks to the S7 compound.
While this may not be new to HugeSupplements, they've used it in their original formula of Pump Serum, pomegranate has a wide range of benefits that is highly underrated.
When it comes to pumps, pomegranates are widely known for their benefits to increase nitric oxide levels [28, 29, 30, 31, 32], improving blood flow  and reducing blood pressure .
Studies using animals found that pomegranate fruit extract and juice can reduce inflammation in veins and can elevate nitrate as well as plasma nitrate levels. 
The antioxidants found in pomegranates, including ursolic acid, oleanolic and gallic acids play an important role in increasing eNOS levels. 
Pomegranate has benefits for both long and short term for increasing blood flow. 
Not only is it great for blood flow but it can also improve recovery and reduce soreness. 
Luckily, HugeSupplements is specifically using an pomegranate extract that's standardized for 40% ellagic acid.
Going beyond pumps, ellagic acid has been shown to increase the production of urolithin B, a compound that can increase mTOR signling and muscle protein synthesis. 
This means the 1 gram of pomegranate is yielding 400mg of ellagic acid, which is more than what you'll see in other supplements containing pomegranate extract.
Another interesting ingredient with research backed benefits is VasoDrive-AP.
This is a combination of two lacto-tri-peptides named isoleucyl-prolyl-proline (IPP) and valyl-prolyl-proline (VPP).
It's extracted from casein milk and each one is a combination of three amino acids.
It works by inhibiting ACE (agiotensin converting enzyme). [37, 38]
ACE is problematic because it can cause vasoconstriction. 
By inhibiting ACE, it can actually increase vasodilation, having a opposite effect as it can reverse vasoconstriction. 
With over 30 studies of these two compounds, there's no doubt that you'll have increased vasodilation and pumps.
All of these studies have been used in a peer reviewed meta analysis done in 2015. 
When it comes to playing defense in nitric oxide, agmatine is the best.
But for defense against reducing acetylcholine levels, huperzine A is the go to. 
Huperzine can improve cognitive function and learning. 
Chances are, you'll be stacking Pump Serum with a pre workout that has some form of choline, so it'll have a synergic effect.
But even if you're not, huperzine can increase mental function well on it's own.
Luckily there is a 980mg dose of choline, which will help increase acetylcholine production while huperzine will prevent the breakdown.
Huperzine can also protect neuronal mitochondria from oxidative stress, which can help maintain and improve mental abilities. 
BioPerine may be the last ingredient but it plays one of the most important roles in supplements.
BioPerine can enhance the bioavailability of all the ingredients in the supplement.
It can do this by inhibiting the stomach enzymes that break down the ingredients before they can reach the intestine.
BioPerine also plays a role in improving glucose uptake by muscle tissue which is what is needed for muscle growth. 
It can also improve insulin sensitivity and help reduce fatty liver symptoms. 
Since it has a spicy taste, it's usually not used in powder supplements but luckily it's here to help you absorb all the ingredients found in Pump Serum.
With over 30g of ingredients, this is a pump formula that is unmatched across the board.
It's formula is full of ergogenic aids and nitric oxide boosters.
With all angles covered, this engages the pump from multiple faucets.
From vasodilation, increased water retention and more, it'll help you look much fuller.