When it comes to aromatase inhibtors, you'll often see Arimistane recommended.
It's chemical name is Androsta-3,5-diene-7,17-dione and because it's an over the counter ingredient, it's easily obtainable.
Because of it's strong anti estrogen effects, it's one of the few AI's that can be obtained without a prescription.
It's used by bodybuilders and athletes to help lower and control estrogen, especially after a suppressive cycle.
Effective at decreasing estrogen
Affordable ingredient to get
Easily obtainable but banned by the WADA
Easy to find
You've probably seen Arimistane around.
It's used in test boosters and PCT supplements to help inhibit estrogen.
Because of it's strong anti-estrogen effects, it can harden and give a dry look to muscles so it's often used during cutting phases.
Although it can be bought over the counter, it's a banned substance by the World Anti-Doping Agency (WADA) since 2017.
Arimistane is often referred to as a prohormone because of it's structure.
It's structure is similar to 7-oxoprasterone and 7-Keto-DHEA or 7-Ketodehydroepiandrosterone.
The difference between Arimistane and those substances is that Arimistane is an aromatase inhibitor while 7-Keto is used for fat loss and muscle building.
And like Arimistane, 7-Keto is banned by the WADA.
What Does Arimistane Do?
Most AI's will inhibit estrogen only while it's used.
However Arimistane can block estrogen even long after it's used.
It's an irreversible AI.
Biosynthesis of estrogen won't occur because Arimistane can suppress the aromatase enzyme.
The benefit of this is that you won't experience a estrogen rebound after you use it.
It'll also indirectly boost testosterone by increasing the production of luteinizing hormone (LH).
Another way it'll help testosterone is by decreasing cortisol levels. Research and studies have demonstrated a link between lowered testosterone levels from high cortisol levels.
Having high estrogen levels means you'll likely be more bloated, especially if you take anabolic steroids or even SARMs.
This is why Arimistane can help your physique look more dry and harder.
And for this, it can be used during cycles of suppressive hormones.
Since Arimistane can lower cortisol and help boost testosterone production, it'll have some benefit for muscle building as well.
However the downside to Arimistane is that it's a gray area substance.
The FDA once warned a company to not use Arimistane in their supplements because it isn't an approved ingredient to use as it should be either a herb, amino acid, vitamin, or some other botanical.
Although it's not allowed to be used as an ingredient in the USA, you can still find this in supplements easily.
Here are the benefits of Arimistane:
- Decreases cortisol
- Boosts testosterone production
- Makes physique harder and drier
- Decreases fat storage
- Blocks estrogen
These benefits make Arimistane not only useful as a PCT ingredient but also as a fat loss agent and a potential muscle builder.
PCT with Arimistane
Arimistane is popularly used as a post cycle thearpy ingredient for when you've done a suppressive cycle, either with prohormones, SARMs or steroids.
Because taking a cycle can suppress your natural hormone production, your levels of estrogen can increase and without a PCT, your testosterone may take longer to recover.
And usually after a cycle, a big portion of the gains and strength will be lost.
But with Arimistane, it's a potent agent for blocking estrogen, helping maintain the gains and can give the body a better chance of recovering it's natural hormone production.
Arimistane is easily obtainable and is one of the best PCT ingredients to use.
And it'll likely be in a supplement that has other ingredients.
Typically a PCT supplement will have a dosage of 50-100mg of Arimistane along with other ingredients that help with cortisol, organ support and testosterone production.
Typically these ingredients will include:
- Ashwagandha (KSM-66 or Shoden or has some standardization for withanolides)
- D-Aspartic Acid (testosterone support)
- Tribulus or Safed Musli (libido support)
- Boron Citrate
- Vitamin D3
A perfect supplement with these ingredients is Rebirth PCT, I recommend it as it's very strong.
A potent PCT stack can also have a testosterone booster, like this one.
Any PCT supplement that you go with should be fully disclosed, contain the best ingredients at proper clinical dosages and has a fair price.
Users report maintaining gains after using Arimistane and fat loss, which isn't surprising.
And since Arimistane is very mild, it isn't as potent as prescription AI's, the side effects are few to none.
There are no reported side effects but there isn't a ton of research on this either.
And bodybuilders who use this as a PCT are less likely to openly share their experience with it.
The longest run study was 8 weeks with 16 weight trained males and they reported no side effects.
If you do experience side effects, like racing heart rate, vomiting, dizziness, then it's often advised to discontinue use.
I've never heard of side effects from using Arimistane, other than the odd case of dry joints but that usually goes away after ending use.
It's smart to keep the dose low, between 50mg to 100mg and no longer than 4-8 weeks at a time.
Testosterone Booster with Arimistane
It would make sense to see Arimistane in a testosterone booster because of it's ability to increase overall test.
Since it stops test from turning into estrogen, Arimistane can better balance your hormone levels.
It inhibits and practically kills off estrogen enzymes even after ending use, which is why they call Arimistane a suicidal anti aromatase.
With high testosterone levels, comes better results for muscle building and motivation.
Estrogen is natural for men to have but when it raises to a level that it becomes higher than testosterone, then this is when issues can occur.
Having Arimistane in a testosterone booster or as a stand alone can help avoid high estrogen levels.
Not only will low testosterone be a barrier to muscle building, but you'll also have lowered strength, endurance and overall workout performance will suffer.
One big sign of high estrogen levels is being bloated.
This is why steroid users are susceptible to the bloated look, during and after their cycles.
High estrogen levels means more water retention, which can also increase blood pressure, make your physique look worse and more.
Arimistane will help achieve that hard and dry look by reducing estrogen levels and water retention.
By using Arimistane, you'll continue controlling estrogen even after ending use and it'll keep blocking estrogen.
It would be wise to use Arimistane in a testosterone booster that has other ingredients.
When it's combined with other ingredients, it becomes an unstoppable natural source of higher testosterone levels and lowered estrogen levels.
Here's some ingredients that are typically used along Arimistane in a testosterone booster:
- Vitamin D3
- ByroViron extract
- Ashwagandha (KSM-66 or Shoden)
- Tongkat (also known as Longjack)
- Shilajit (PrimaVie)
- Boron Citrate
- Mucuna Pruriens
The combination of any of these ingredients with Arimistane will help increase libido, decrease cortisol while helping retain as much muscle as possible gained from a suppressive cycle.
This is why we recommend using the PCT stack, which not only has Arimistane but also all of these ingredients and it can help boost your male hormones while reducing estrogen, which can be useful even if you're not using it for a PCT.
Arimistane vs Arimidex
Arimidex (or anastrozole) is one of the strongest estrogen inhibitors.
But it's an over the counter drug and it's used to treat women with breast cancer.
So with stronger effects come stronger side effects.
Arimidex shouldn't be used and Arimistane is just better as it has no to few side effects (with dry joints being the common complaint which happens with low estrogen).
Can I Use Arimistane in a Stack?
Arimistane is often used in existing blends with other ingredients, like tribulus extract and ashwagandha.
It can be stacked with other muscle builders since it has no side effects and it's only an estrogen inhibitor ingredient.
The best laxogenin supplement we can recommend is Annihilate.
Why Use Arimistane?
When it comes to estrogen blockers, very few compare to Arimistane in terms of safety and efficacy.
Arimistane is a aromatase inhibitor that can block estrogen enzymes, while continue blocking it long after it's usage.
This means you won't experience a rebound after ending supplementation.
And because it can block estrogen, it will allow for testosterone levels to increase.
High estrogen can cause issues in males, including muscle loss, fat gain, water retention, lethargy, and more.
Is Arimistane Legal?
Since Arimistane is not a biotical, herb, vitamin or anything natural, it is considered to be banned by the FDA to be used in supplements.
The FDA defines Arimistane as an over the counter drug, but to this day it's still widely available in supplements.
And it's also banned by the anti-doping agencies so it may lead to issues if you're drug tested or compete competitively.
Some supplements companies will try to put some compound that's similar to DHEA but isn't Arimistane, this is something to look out for.
What's The Best Stack For Arimistane?
Arimistane is often included in pre made blends of supplements.
The results get better when it's included in a muscle building stack.
Some examples of potent muscle building stacks can be found here.
Since Arimistane has little to no side effects, it can be used alongside any natural ingredient or herb like ashwagandha, shilajit or mucuna pruriens.
The PCT stack is the best you can get for all around testosterone and estrogen control.
Is Arimistane The Best PCT?
As far as safety and benefits, Arimistane is easily the best and we can recommend this 100%.
It's often used as a PCT for steroids but since prohormones are much more harsh, usually a PCT like Clomid with Arimidex are used instead.
It's best to consult your doctor if you think you need to use an over the counter estrogen inhibitor.
Other Supplements with Arimistane
When Arimistane is used it can block estrogen and even after ending use, estrogen won't rebound unlike other AI's.
So with this in mind, it's best to combine Arimistane with other ingredients.
There are some stand alone Arimistane supplements like Hi-Tech but you won't be getting the best bang for your buck.
Other supplements include:
- Hi-Tech Arimistane (60 servings of 50mg)
- Apollon Nutrition Hard Target (Testosterone booster with Laxogenin and Arimistane)
You can use discount code FITFREK for any of the products we recommend.
Arimistane: The Best Estrogen Blocker
Blocking estrogen is not the only benefit that Arimistane has.
But it can prevent it from rebounding after using, making it one of the most useful ingredients in a PCT supplement.