Let's face it, the fitness world is practically swimming in anabolic steroids.

Originally designed as a lifeline for folks dealing with muscle loss, steroids have become the go-to for anyone looking to beef up their muscle mass, strength, and bone density.

But here's the thing:

Steroids come with a laundry list of side effects.

And guess who gets the short end of the stick?

Yep, women and children.

This led to a chorus of doctors asking for a safer alternative that could still deliver the goods in terms of muscle growth but without the nasty side effects.

Enter stage right: SARMs, or Selective Androgen Receptor Modulators.

These guys are a game-changer, and here's why:

Unlike steroids, which bind to every androgen receptor they can find (leading to unwanted side effects like prostate growth), SARMs are a bit more discerning.

They only bind to muscle and bone tissue, which means fewer androgenic side effects.

While SARMs can still have some impact on things like your lipid values, they're not going to wreak the same level of havoc as steroids.

And the cherry on top? SARMs are legal to buy as research chemicals.

Sounds like a win-win, right?

You bet.

Plus, there's a whole smorgasbord of SARMs to choose from, depending on your goals. You can even stack them together or use them with peptides.

Here are a few fan favorites:

• MK-677: While not technically a SARM, this growth hormone secretagogue can boost the amount of growth hormone your body naturally produces. This can lead to improved muscle growth, increased bone density, fat loss, and even better skin and hair.
• Cardarine: Again, not technically a SARM, but it's a great tool for improving fat loss, cholesterol, endurance, and more.
• Ligandrol-4033: This is the go-to SARM for most people looking to increase muscle size and strength. It's generally well-tolerated, and users often see great results.

In general, most people get along just fine with SARMs.

Of course, there are always exceptions, and some folks might have reactions to the stronger SARMs.

But don't worry, we've got you covered.

Whatever you want to know about SARMs, we've done the homework...

SARMs are a novel class of drugs similar to androgenic steroids, including testosterone.

They aren't steroids, but they do bind to the androgen receptors located in our cells, which respond to hormones like testosterone.

The appeal of SARMs is they have the ability to stimulate the androgen receptor just like anabolic steroids, but they don’t produce the same side effects.

This is a huge advancement in the world of bodybuilding and fitness.

They were initially discovered during a drug development trial aiming to find a treatment for prostate cancer.

Some commonly used SARMs include Ostarine (MK-2866), Cardarine (GW501516), and Ibutamoren (MK-667) [source].

When it comes to the world of fitness and bodybuilding, SARMs are like the new kids on the block.

They're making waves because of their unique way of working.

Unlike steroids, which are a bit like a bull in a china shop, binding to every androgen receptor they come across, SARMs are more like a well-trained ballet dancer, selectively binding to only muscle and bone tissue [study, study].

This selective binding is what makes SARMs so special. They can stimulate muscle-building receptors while avoiding other receptors that could lead to androgenic side effects [study] .

This means you get the muscle and bone-building benefits without the unwanted extras.

The journey of SARMs started back in the 1940s with the initial efforts to develop steroidal SARMs, which were based on modifications of the testosterone molecule [study, study].

However, the real game-changer came in the late 1990s when the first nonsteroidal SARM, an analog of bicalutamide, was discovered [study].

These nonsteroidal SARMs were designed to have the same kind of effects as androgenic drugs, such as anabolic-androgenic steroids, but with more selectivity in their action [study].

This marked the beginning of a new era in the field of performance-enhancing drugs.

The development of nonsteroidal SARMs was further propelled by independent work at Ligand Pharmaceuticals and the University of Tennessee [study].

Since then, SARMs have been studied for various applications, including as potential treatments for diseases like muscle wasting, breast cancer, and osteoporosis [study].

There are many different types of SARMs, each with its own potential benefits and side effects.

Some of the most common ones include:

• Ostarine (MK-2866): Known for its mild nature and versatility, Ostarine is often recommended for beginners. It can promote muscle growth and fat loss without causing significant side effects.

• Ligandrol (LGD-4033): Ligandrol is a more potent SARM that is best suited for bulking cycles. It can significantly increase muscle mass, but it may also cause more noticeable side effects.

• Testolone (RAD-140): Testolone is one of the most potent SARMs available. It can lead to significant muscle growth and has even been studied for its potential to combat muscle-wasting diseases.

Here is more information on the common types of SARMs:

Ostarine (MK-2866):

Ostarine, also known as MK-2866, is one of the most well-known and widely used SARMs.

It's known for its mild nature and versatility, making it a popular choice for beginners.

Ostarine primarily targets muscle and bone tissue, promoting muscle growth and bone strength. It's also been noted for its potential to aid in fat loss.

The typical dosage for Ostarine ranges from 10-30mg per day, and it's often used in cycles of 8-12 weeks.

Ligandrol (LGD-4033):

Ligandrol, or LGD-4033, is a more potent SARM that's best suited for bulking cycles.

It's known for its ability to significantly increase muscle mass and strength.

Ligandrol works by binding to androgen receptors in the muscles and bones, stimulating the growth of new muscle cells and enhancing bone mineral density.

The usual dosage for Ligandrol is between 5-10mg per day, and it's typically used in cycles of 8-12 weeks.

Testolone (RAD-140):

Testolone, also known as RAD-140, is one of the most potent SARMs available.

It's known for its ability to promote significant muscle growth and has even been studied for its potential to combat muscle-wasting diseases.

Testolone works by selectively binding to androgen receptors in the muscles and bones, leading to increased muscle mass and bone strength. The typical dosage for Testolone is between 10-30mg per day, and it's often used in cycles of 8-12 weeks.

MK-677 (Ibutamoren):

While technically not a SARM, MK-677, also known as Ibutamoren, is often grouped with SARMs due to its similar effects. MK-677 is a growth hormone secretagogue, which means it stimulates the body to produce more growth hormones.

This can lead to increased muscle growth, improved bone density, and fat loss. The typical dosage for MK-677 is between 10-25mg per day, and it can be used in longer cycles of up to 6 months due to its different mechanisms of action.

Cardarine (GW-501516):

Again, not technically a SARM, but often discussed in the same context, Cardarine, or GW-501516, is known for its ability to improve fat loss, cholesterol levels, and endurance.

It works by activating the PPARδ receptor, which increases the body's use of fat for energy.

This can lead to improved fat loss and increased endurance, making Cardarine a popular choice for cutting cycles and endurance athletes.

The typical dosage for Cardarine is between 10-20mg per day, and it's often used in cycles of 8-12 weeks.

Research on SARMs has shown promising results. Here are some key findings:

1. A study published in JAMA showed that the majority of unapproved drugs marketed as SARMs were inaccurately labeled and contained unapproved drugs and substances.

2. A study published in the Asian Journal of Andrology stated that SARMs show promise in the treatment of a variety of clinical indications, including muscle-wasting diseases.

3. A study published in the Journal ofPharmacology and Experimental Therapeutics found that SARMs have the potential to be used in therapy for diseases such as cancer cachexia, osteoporosis, frailty, and other signs of aging.

4. A study published in Current Opinion in Supportive and Palliative Care found that SARMs could be used to prevent and treat muscle wasting in patients with cancer.

Here's how you can use SARMs safely and effectively:

1. Choose the Right SARM: Not all SARMs are created equal. Some are more potent and have a higher risk of side effects than others. For example, Ostarine (MK-2866) is often recommended for beginners due to its mild nature, while Ligandrol (LGD-4033) is more potent and may be suitable for more experienced users. Study

2. Start with a Low Dose: It's always a good idea to start with a low dose to see how your body reacts. If you tolerate the SARM well, you can gradually increase the dose. However, keep in mind that higher doses are more likely to cause side effects. Study

3. Cycle Your Use: Continuous use of SARMs can lead to side effects like suppression of natural testosterone production. To avoid this, it's recommended to use SARMs in cycles, typically 8-12 weeks, followed by a break. This gives your body a chance to recover. Study

4. Monitor Your Health: Regular health check-ups are crucial when using SARMs. This includes blood tests to monitor your liver health and hormone levels. If you notice any adverse effects, it's best to stop using SARMs and seek medical advice. Study

5. Maintain a Healthy Lifestyle: SARMs are not a magic pill. They work best when combined with a healthy diet and regular exercise. Also, getting enough sleep and reducing stress can enhance your results. Study

6. Avoid Stacking: Stacking refers to the practice of using multiple SARMs at the same time. While this can potentially lead to greater muscle gains, it also increases the risk of side effects. If you're new to SARMs, it's best to stick to one at a time. Study

Remember, while SARMs can help enhance muscle growth and fat loss, they are not without risks. Always do your research, listen to your body, and consult with a healthcare professional before starting any new supplement regimen.

If you're a natural lifter, you'll want to hit the gym more often.

Aiming to work for each muscle group twice a week is a good starting point, but if you're looking to see significant growth beyond the beginner stage, you might want to up that to three or even four times a week. 

If you're an enhanced lifter, you've got a bit of a free pass here.

Thanks to the protein synthesis boost from your enhancements, you don't need to work on each muscle group quite as often.

Cardio, Anyone?

If you're an enhanced lifter, it's time to embrace cardio. It's a great way to counteract some of the less-than-ideal health impacts that can come with enhancements, like high blood pressure and cholesterol levels.

Volume Control

If you're a natural lifter, you'll want to keep an eye on your volume. Why? Because you're more susceptible to the effects of cortisol. This pesky hormone can ramp up protein breakdown and put a damper on protein synthesis.

Effort Level

Natural lifters, it's time to push it. To stimulate maximum growth, you'll need to work harder during each set. You might not be able to do as much volume, but you can make up for it with effort.

Protein Power

Enhanced lifters, listen up. You'll need more protein. Thanks to your elevated rate of protein synthesis, you'll need to keep the protein coming in.

Calorie Count

If you're in a growth phase and you're an enhanced lifter, you'll need more calories. Your body is a pro at using nutrients efficiently to build muscle, so feed it what it needs.

Cortisol Check

Natural lifters, it's time to focus on decreasing cortisol levels. Lower cortisol levels can help promote growth, so it's worth paying attention to.

Supplement Situation

Enhanced lifters, you'll want to stock up on supplements. Especially the ones that boost health. They can help offset some of the potential negative effects of performance-enhancing drugs.

Calorie Cutting

If you're an enhanced lifter and you're dieting, you can afford to cut back on calories a bit. You're less likely to lose muscle, so you can be a bit more aggressive with your calorie deficit.

Exercise Excellence

Natural lifters, it's all about quality over quantity. Focus on the most effective exercises and avoid doing too many similar ones. You want to get the most bang for your buck with each workout.

Reddit is a great place to find real user experiences with SARMs. Here are some experiences shared by Reddit users:

1. "u/No-Ad-4457" shared their positive experience with RAD140, noting significant strength gains and improved physique.

2. "u/ifbbprodj" also had a positive experience with RAD140, with noticeable muscle gains and fat loss.

3. "u/ViewNo2652" reported a positive experience with RAD140 but also noted some side effects like aggression and mood swings.

4. "u/benmill6" asked for experiences with RAD140 and received mixed responses, with some users reporting positive results and others noting side effects like hair loss and suppression.

5. "u/7HVN" asked for a straight answer on SARMs and received a variety of responses, with some users advocating for their use and others warning against potential side effects.

6. "u/Jorzaz" asked if SARMs are worth it and received mixed responses, with some users believing they are a good stepping stone to more potent substances, while others believe they are not worth the cost and potential side effects.

7. "u/Imfear2000" asked for advice on SARMs or a test cycle and received a variety of responses, with some users recommending SARMs for beginners and others suggesting a test cycle instead.

8. "u/Findyourbeach720" shared their transformation after using SARMs, receiving positive feedback from the community.

Alright, let's talk about the not-so-pretty side of SARMs.

You see, while these compounds have a reputation for muscle-building magic, they're not all sunshine and rainbows.

A study that surveyed the land of Reddit found that over half of SARMs users experienced side effects.

We're talking mood swings, shrunken testicles, and acne. Not exactly the kind of "gains" you're looking for, right?

This survey wasn't just a quick poll either. It collected responses from 520 people, with 343 of them admitting to using SARMs.

Most of these users were guys between 18 and 29. And here's the kicker: over 90% of them bought SARMs online without any medical advice.

Sure, more than 90% of these guys reported muscle growth. But over half of them also reported significant side effects.

This just goes to show that while SARMs might promise muscle growth, they can also deliver a hefty dose of unwanted side effects.

And it's not just Reddit users reporting these issues. The FDA has also raised red flags about SARMs.

They've linked these compounds to serious health problems like an increased risk of heart attack or stroke, hallucinations, and sleep disturbances.

So, while SARMs might seem like a shortcut to gains, they come with a pretty significant risk.

As always, it's crucial to chat with a healthcare professional before diving into a new supplement routine.

Because when it comes to your health, it's always better to be safe than sorry.

SARMs, or Selective Androgen Receptor Modulators, are a big deal in the bodybuilding anabolic category.

They're known for their targeted action and unique benefits.

The primary benefit of SARMs is their potential to promote muscle growth.

By binding to androgen receptors in muscle and bone tissue, SARMs can stimulate the growth of new muscle cells.

This can lead to increased muscle mass and strength, making SARMs a popular choice among bodybuilders and athletes.

Here's a quick rundown:

1. Muscle Growth: SARMs are like personal trainers for your androgen receptors. They stimulate protein synthesis and muscle growth, making them a favorite among bodybuilders and athletes.

2. Bone Health: SARMs aren't just about muscles. They're also champions of bone health, working to increase bone mineral density.

3. Fat Loss: SARMs act like your personal fat-burning furnace. They help increase fat oxidation and reduce body fat, leading to a leaner physique.

4. Fewer Side Effects: Compared to traditional steroids, SARMs have a better side effect profile. They're less likely to cause unwanted effects like acne, hair loss, and prostate enlargement.

SARMs are also a hit among women looking to enhance their fitness and physique.

They can help build lean muscle mass without the risk of virilization, aid in fat loss, and improve bone health.

But remember, ladies, always use SARMs responsibly and under professional guidance.

Post Cycle Therapy (PCT) is crucial after a SARMs cycle.

It helps restore natural hormone levels and can keep side effects like fatigue, loss of libido, and mood changes at bay.

The specifics of PCT can vary, so always consult with a healthcare professional.

(Read: PCT for SARMs)