Top 10 Best Prohormones: Strongest For Muscle Mass Gains And Cutting

By Nader Qudimat ·
Updated Apr 27, 2021

BEST OVERALL

1 Testosterone by Hi-Tech Pharmaceuticals

Want more gains from prohormones?

Then you're in the right place.

Because I'm going to show you the strongest prohormones that work similarly to steroids.

The best part?

All of these prohormones work perfectly in 2021.

Check out our PCT guide to help get you through the post cycles. 

And our on-cycle support guide will help optimize organ function.

(For our favorite estrogen blocker ingredient, check out this Arimistane guide)

See also 1-Andro and Epiandro

And our best deals page sometimes feature great deals on PCT, prohormones, and organ support.

Let's get started:

Contents

Top 10 Strongest Prohormones

1-AD is a 1-Andro (aka 1-DHEA) based prohormone produced by Hi Tech Pharmaceuticals.

1-Andro is one of the few prohormones that is not yet on the FDA’s banned list.

It is one of the most potent prohormones that are still legally available.

In one study, out of Texas A&M, consuming 330 mg of 1-Andro over 4 weeks had the same impact as a 300 mg cycle of injectable Testosterone.

1-AD includes 50 mg per serving of 5a Hydroxy Laxogenin Acetate.

This is a natural but powerful anabolic (aka nature's steroid!) which is derived from plants.

It assists in boosting mass and strength while also inhibiting cortisol levels.

Strength level: 8/10

Side effects: mild

So long as you are taking in plenty of quality protein and working out hard and smart, you will make pleasing mass gains on 1-AD.

However, this is a prohormone designed for experienced bodybuilders.

1-AD will aid as a cutting agent due to its ability to minimize cortisol levels while increasing lean muscle mass.

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Blackstones Labs is a hardcore but trusted company that makes next level supplements.

Brutal 4Ce, their 4-andro supplement, is a formula that contains three different types of 4-DHEA, and the absorption is increased with its liposomal delivery technology.

You get only about 65mg per capsule, but you're also getting 3 forms of 4-andro, which means it'll be more effective.

To get 325mg, you'd need to take at least 5 capsules per day, split between the morning and evening.

This means you'll probably want to get more than one bottle for your cycle.

This is an effective prohormone to take and you can prevent side effects by taking in a proper on-cycle supplement.

If you're in the UK, then you'll like Androtest as a good alternative

Strength level: 8/10

Side effects: mild

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When it comes to hardcore supplements, like borderline legal, Hi-Tech Pharmaceuticals can be depended on. 

This prohormone, Decaboline 19-nor, is a derivative of Deca but has far less side effects, no water retention, and quick gains. 

Strength level: 8/10

Side effects: low

The downside is that there are some side effects but they are manageable with a PCT and / or on-cycle support supplements. 

Decabolin is the perfect choice for those bulking as it'll increase strength and gains at a incredible rate. 

It's not unusual to hear of users making up to 10lbs of gains and massive improvements in strength. 

Some also report joint benefits, this might be due to the enhanced recovery that it provides. 

All in all, Decabolin 19-nor is a great choice for a prohormone. 

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Havoc by RPN is a single ingredient prohormone.

It contains 2a, 3a-epithio-17a-methyl-5a-androstan-17b-ol, which is also known as Epistane.

This muscle building prohormone was released in 2007.

It has gained a reputation as a moderate ‘dry’ prohormone, which is not as ‘harsh’ as some others on the market.

As such, it is more ideally suited to beginner and intermediate bodybuilders.

Epistane is an anti-estrogenic prohormone, meaning that it will not aromatize.

It will boost the body’s natural production of testosterone, leading to more muscle mass, less fat and enhanced libido.

You will not experience an increase in water retention when taking Havoc.

Strength level: 8/10

Side effects: mild 

Though your gains may not be as pronounced on Havoc as on some of the more extreme prohormones, you can expect to make substantial gains in lean mass, provided that you are training heavy and eating right.

If you are on a bulking diet, you can expect to gain 6-8 pounds of dry muscle, while also stripping off body fat over an 8-week cycle at 20-40 mg per day.

You should follow a post cycle therapy regime of 8 weeks.

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Chosen 1 contains a 65mg blend of 1-DHEA.

1-DHEA is a precursor to 1-testosterone, a potent hormone that leads to more lean muscle gains and increased aggression in the gym. 

It's often compared to the banned compound epistane, making it a great choice for those living in the states if you can't get your hands on Havoc by RPN. 

Strength level: 7/10

Side effects: low

Users report more dry gains but with few side effects like headaches, increased anxiety, back pumps and testosterone suppression. 

Most of these can be prevented with a PCT supplement. 

It isn't toxic towards organs and it is legal as of today but we don't know how long that'll last. 

Read our review on Chosen1 here.

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1-Testosterone is a muscle building prohormone that contains the highest level of 1-Andro of any product on the market.

1-Andro is a naturally occurring metabolite that is unable to convert to estrogen.

In a recent study, released in the Journal of Applied Physiology, 1-andro was as potent as testosterone enanthate, the gold standard for testosterone products.

In another study, out of West Texas A&M University, participants who were given 1-Andro gained an average lean mass of 10.4 pounds and an increase of 92.2 pounds in total load in the bench, squat and deadlift, the researchers concluded that the prohormone contributed to robust improvements in muscle mass and strength in resistance-trained individuals.

1-Testostosterone includes the Cyclosome Delivery System, which increases the bioavailability and effectiveness of prohormone compounds by undergoing cyclodextrin prior to lipid encapsulation.

This has been shown to improve bioavailability by an incredible 90%.

Reported side effects of this prohormone includes nausea, bloating and vomiting.

Strength level: 8/10

Side effects: mild

1-Testosterone has been shown to be 7 times more anabolic than testosterone.

It will lead to rapid increases in dry lean muscle mass, that are sustainable after a cycle.

Because 1-Andro does not convert to estrogen, there is no problem with water retention when taking this product. Another upside is that it will also increase your fat burning capacity.

Another option is Metha Quad, a prohormone that contains 4 types of andro-based compounds, and it's a best seller.

Use a PCT support like this one

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Gaspari once had the crown for having the best prohormone back in 2005, but since then Halodrol has been reformulated to keep it legal. 

Hi-Tech has rebranded and reformulated Halodrol and turned it back into what was once known as a hard prohormone. 

Strength: 9/10

Side effects: low

Halodrol packs 5 hardcore prohormones into a small package.

It has 1-andro, a prohormone that converts into testosterone. 

While it can improve body composition as one study shows, it can be a bit harsh on the organs. 

Next is 4-andro, also known as 4-AD, research shows it can increase testosterone, providing the body an anabolic environment for muscle growth but it does come with risk of increasing estrogen. 

Androsterone is pine pollen and it converts into DHT (dihydrotestosterone) and it's known to be more androgenic than testosterone. This will help with recovery and muscle growth but with the downside that comes with increased DHT levels is that it can cause baldness.

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Huge Nutrition has one of the best anabolic stacks we've tried so far. 

It's two supplements, Sapogenix and Ecdysterone, and they contain the strongest plant-based anabolic steroids you can ask for. 

Check out our review on Sapogenix here. 

And you can see how Ecdysterone is more potent than Dianabol (steroid) and a few SARMs in this article here

Strength level: 8.5/10

Side effects: none

The combination of these two potent supplements can increase workout performance, gains and strength without the dangerous side effects that synthetic prohormones brings.

And the best part is that it's legal worldwide, with free shipping as well (when you spend $100 or more).

So while prohormones require you to cycle off and suffer the side effects of low test, this will just help you gain muscle and strength, without suffering afterwards. 

You can check out the studies and research behind these two supplements in our legal steroid guide

These two are also great choices for PCT, and can be combined with any other anabolic for even better and more gains. 

Hi-Tech Pharmaceuticals even uses the same extract, Dioscorea Makino, in their Diosterol and it's used in Monster Plexx, which has plenty of reviews published as well.  

And Huge Nutrition uses the same absorption enhancing technology that they are using for both of these, Sapogenix and Ecdysterone.

It's also used in Dianabol by Hi-Tech.

Hi-Tech has a comparable stack called the Anavar and Dianabol stack, but Anavar is a prohormone that may come with side effects.

These two run better when it's used in a 8 week cycle, but you'll still see great results after just 4 weeks.

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Superdrol is made out of 4 main compounds that help remove water while building muscle.

Strength level: 9/10
Side effects: mild

Hi-Tech is using it's delivery system to help optimize absorption with these ingredients.

The 4 anabolic ingredients are combined with natural herbs to maximize the gains from allangles.

It includes 1-andro, 4-andro, androsterone, androstenolone, and even turkesterone.

This combination, while already potent, would be even better if it was combined with Sapogenix.

Sapogenix is the superior form of Laxogenin as it uses the most anabolic forms of plant-based steroids, which will work together to help increase strength and muscle growth.

Because of how strong Superdrol is, users are referring it as the super Anadrol, which is an anabolic steroid. 

Expect strength gains, aggression and fat burning with Superdrol. 

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Here's alternative sources:

If you're planning to stack Superdrol with Monster Plexx, I would recommend sticking to the very minimum of dosing and only increase to full dosing if after 2-3 weeks you are not seeing improvements. 

While Plexx and Superdrol look similar, there's a key difference between them and that's Superdrol that has more prohormones while Plexx contains more natural herbs but also has prohormones. 

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If you're in the States, then your best choice is Halodrol or 1-Testosterone because it's ruled by the FDA to not be a dietary ingredient. 

Nanadrol is built around methylstenbolone, a DHT derived prohormone that has been proven to provide solid lean mass gains without water retention.

The methylstenbolone in Nanodrol has been broken down into particles that are less than 200nm in diameter.

This is a thousand times smaller than the methylstenbolone that is found in other products such as Ultradrol.

This makes it far faster absorbing and more bioavailable.

However Nanodrol does cause some stress to organs like Liver and we recommend using a PCT / on-cycle supplement. 

In fact, there's a pre made stack with Nanodrol that Predator sells that you can find here

Strength level: 9/10

Side effects: harsh

You will experience substantial strength and mass gains when supplementing with Nanodrol.

It can also be used in a recomp or cutting cycle.

Use a test booster along or afterwards like this one

After an 8-week cycle, you should follow a PCT cycle for another 8 weeks.

You should take an on-cycle support supplement for as much protection as possible.

Nanodrol is best taken while on a bulking diet, in which you are consuming excess clean calories.

On such a protocol, combined with hard out training, you may be able to gain up to 15 pounds in a 4 week cycle at 12 mg per dose.

For cycle support from the UK, get Defend (spending over $100 will get you free shipping from this store).

Or a comprehensive (but expensive) supplement like these ones works as well. 

You can check out the reviews on a estrogen blocker like this one.  

If you want similar products without side effects, basically almost like legal steroids, check out this list

Combining Nanodrol or any prohormone with one of these muscle building stacks would result in some really good synergy for gains. 

A good alternative to Nanodrol is Nano-1t as it is more mild in side effects but still strong. 

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Prohormones Buying Guide:

You’re here to make gains…

By now, you think you've tried everything.

You’re training hard, eating right, and it’s been ages since you’ve seen any real progress.

Now you probably have tried different things and taken your time to assess your past performance to improve future performance, and maybe even adjusted your diet as it may not be the best.

The last thing you want to do is go for a prohormone as that can get you on a path that can be very difficult to get off of.

And if you've considered SARMs then you know there's plenty of options to choose from before choosing the hardcore path of prohormones.

Prohormones can be very risky but the rewards can be amazing if it’s done right.

With the right stack, you can absolutely break through walls of plateau’s like never before.

But again, this category of supplements is only for those who really need to take their physiques to the next level.

Use a pre workout like Bulk or Wrecked help with workout performance..

Or try combining a testosterone booster for the ultimate muscle building stack. 

Assuming you know what you’re doing and have done your research, then go on and check out these top 10 prohormone supplements.

Otherwise, stick to a solid pre workout, maybe even consider a natural plant-based steroid supplement or our list for laxogenin before looking at these prohormones.

Remember, this category is very gray-area like, and it was hard enough to rank them in a top 10 style as they differ in strength and are not for everyone. 

Do your research and avoid these supplements if you are a beginner or under 25 years old and most importantly, ask your doctor and get approval before using any supplement.

You can also stack a prohormone supplement with a natural anabolic like Laxogenin and epicatechin. 

Make your own pre workout by buying stimulants in bulk from BulkStimulants like DMAA and DMHA.

What Are The Types Of Prohormones Available?

These are the popular prohormone compounds available on the market.

The ones that convert to testosterone:

  • 4–androstenedione
  • 4-androstenediol 
  • 1-DHEA (1-androsterone): converts t 1-testosterone

And these convert to nortestosterone:

  • 19-norandrostenedione
  • 19-norandrostenediol

Best Prohormone Stacks For Beginners and Advanced Users:

Remember to use a PCT, and an on-cycle support supplement as stacking prohormones can be very harsh on the organs and on your hormone system. 

Reviews are published and shared on this page.

For beginners:

For advanced users

Best for both advanced and beginners:

One interesting anabolic that may make this list is Monster Plexx

Another option is the LG Science Bulking Kit, this is one of the most advanced prohormone stacks and the reviews will give you an idea of what kind of results to expect.

For more muscle building stacks, check out this list. 

You can read our review on Sapogenix here. 

Are Prohormone's Safe?

Generally, they are safe but like any supplement, using too much or for too long can result in harsh side effects. 

These are oral supplements that interact with your hormones, and some of these have worse side effects than others. 

Each product we listed have a rated for side effects.

Low meaning there's little to no side effects, mild means there's some side effects but it's manageable, and harsh is the worst and that's where even with on-cycle supplements, it get's risky and hard on your organs / hormone system. 

Following the direction of the prohormone, cycling, and using a PCT / on-cycle can help minimize and reduce the side effects.

What Are The Side Effects of Prohormones?

The effects of prohormones, even the harsh ones, should subside after ending your cycle. 

But again, this process should involve a PCT and an on-cycle support supplement. 

Check out these two articles:

The side effects can vary but generally, anything that can suppress your hormones (i.e. testosterone), can mess with sleep, elevate cholesterol levels, organ damage, hair loss, acne, oily skin and more. 

Recommended Prohormone Cycle and Dosage

Every compound is different. 

The general rule of thumb is that the smaller the recommended dose, the stronger the prohormone will be. 

Generally cycles will last anywhere from 4 to 8 weeks. 

More is not always better because once you come off, your natural hormone system will be shut down (depending on the prohormone) and you'll take some time to return back to normal. 

Most people will advise to staying at 3 cycles or less per year, and we think this is good advice. 

You'll want to spend anywhere from 4 to 12 weeks for post cycle therapy after your cycle, depending on the harshness of the chemical and how you feel after. 

Is PCT Necessary?

If you weren't taking prohormones, we'd still recommend looking into a PCT or a testosterone boosters as they contain vitamins and minerals that most men are deficient in.

When you take a prohormones, they not only shut down your hormone system but they suppress them after the cycle. 

So if you're deficent in these minerals and vitamins, it'll be that much harder for your body to return back to normal. 

Check out our post cycle therapy guide here

By not taking a PCT, your risking body and organs as it'll be more likely to retain water, you'll likely gynecomastia, and your prostate is likely to enlarge. 

When you're using prohormones, your estrogen levels may increase, especially after the cycle.

A good PCT supplement will help reduce estrogen levels and may help your hormone system boot back to normal quicker. 

The best on cycle support supplement is coming up…

Best On-Cycle Support: Defend by Huge Nutrition

When you're taking something as strong as these prohormones, it's recommended to use a on-cycle supplement for complete protection, as well as a PCT like this one.

Defend is an excellent choice as it contains 7 strong and fully dosed ingredients that will help protect and strengthen your organs.

We talk about how Defend is better than your other choices for cycle support here.

It starts with a big 1 gram milk thistle extract and this ingredient has been used to protect against liver damage for years now.

The active ingredient here is Silymarin and it is an excellent antioxidant.

Various studies show it's protection against toxins in the liver and it's one of the ingredients that you should always see in a cycle support supplement.

Another crucial ingredient to have is NAC, N-Acetyl-Cysteine, which helps detoxify the liver and can even reverse and treat damage done to the liver. And some research shows it can also improve liver function.

The rest of the ingredients have various benefits from being anti inflammatory to helping aid stomach digestion and treat high cholesterol while improving the lipid profile.

Defend and it's profile of ingredients are important to have during a cycle.

Huge Nutrition is also a great source of supplements as their supplements are fully transparent, from their Wrecked pre workout to their plant-based natural steroid supplements.

They also have a PCT stack for optimal testosterone production and cycle support.

Use coupon code FITFREK for 10% off.

Huge Nutrition has excellent shipping options, including free international if you order $100 or more.

You can see more on-cycle supplements here.  

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The Future of Prohormones

Prohormones have proven to be an effective way to increase muscle mass.

Supplement companies are continuously coming out with new blends, and they sometimes use new designer compounds, but this can be risky since the long term health effects are unknown. 

This is why you need to stick to a short cycle of 4 weeks, twice, max 3 times a year. 

There's no reason to risk your health over a few pounds as the short term harshness of prohormones isn't worth the trouble for the months of possible side effects that you may endure. 

This is why we keep recommending Sapogenix, and the similar legal steroid supplements that are available. 

These are super potent anabolics but have zero side effects.

If you have any questions, feel free to leave a comment below or contact me

14 thoughts on “Top 10 Best Prohormones: Strongest For Muscle Mass Gains And Cutting”

    • Hi Steve

      I don’t know personally, but there’s not much human research on Laxogenin supps.

      I would suggest going with Ep1logue, which has a similar profile but more reviews and I personally made some gains with it.

      Laxo is mainly hype so far, and Ep1logue is potent and lots of people are reporting gains with it.

      Reply
  1. I jumped on a 4week cycle of nanodrol and all I can say is WOW!. Completely Savage man. After two weeks of use I packed on 20lbs of lean muscle. I’m rounding the final week of my month cycle ATM and just completely blown away by this product. I’m 37yo and have been lifting natural since 21.

    Reply
    • Hey Robbie, it’s strong stuff! I’m impressed by your results. I know 10lbs would be lucky, but 20!

      Did you gain any fat along with the muscle? How much were you using and what sort of workouts were you doing?

      Reply
        • Hi Brian, it’s recommended to take a cycle support supplement.

          Use a post cycle supplement. The number 1 prohormone, Nanodrol is methylated and it is taxing on the liver. So a on-cycle and post cycle supplement will do wonders in reducing the side effects.

          I also recommend joint support especially with something like Nanodrol.

          Stay safe!

          Reply
  2. Hi guys,
    I am a recurring user of prohormones ( 10 cycles at least) and nanodrol is definitely not the best choice. I have made two cycles with this product, made some gains but nothing transcendent. And as a bonus this product is expensive. For me, the best prohormone is without a doubt our good old … Superdrol if we can tame the beast.
    Headaches due toblood pressure for 3/4 days, cramps (at least during the first cycle), lethargy (during the first cycle too). Need a high protein/high carb/ low fat diet, to supplement with coenzyme q10, red yeast rice, liv52, tudca, to make a good pct. But the gains are there and the product is not very expensive. Not for beginners. I still have to try the M1T which seems to be a killer.

    Reply

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