Is It Okay To Take DMAA?

by Nader Qudimat
Updated July 13, 2023

DMAA, also known as 1,3-dimethylamylamine, is a compound used in various dietary supplements due to its potential benefits.

This article aims to answer whether it's okay to take DMAA and provide a comprehensive overview of DMAA, including its benefits, potential risks, and controversies surrounding its use.

We'll dive into the scientific studies that have explored DMAA's effects and provide a balanced view of this compound.

Is It Okay To Take DMAA: Quick Overview

Based on the available scientific literature, DMAA can be safe for healthy individuals who adhere to the recommended dosages.

Studies show that DMAA is safe for healthy individuals at 90mg or less doses.

What Is DMAA?

1,3-Dimethylamylamine, or DMAA, is a compound originally developed as a nasal decongestant but has since gained popularity as a pre-workout and weight-loss supplement.

It also goes with other names, such as methylhexanamine and geranium extract.

DMAA is known for its stimulant properties, providing users with increased energy and focus.

(Recommended reading: What Is DMAA Pre-Workout?)

The Science Behind DMAA

DMAA works by constricting blood vessels and arteries, which can lead to an increase in blood pressure.

This constriction also leads to decreased blood flow, which can cause the heart to work harder.

This is why DMAA is often used in pre-workout supplements - the increased heart rate and blood pressure can lead to increased intensity in workouts.

The Benefits Of DMAA

When used responsibly, DMAA can provide several benefits.

These include increased energy, improved focus, and enhanced athletic performance.

It's also been used for weight loss due to its ability to suppress appetite.

However, it's important to note that these benefits can come with risks, especially when taken in high doses. Read more about how DMAA feels here.

Benefits Of DMAA

DMAA, also known as 1,3-dimethylamylamine, is a compound used in various dietary supplements for its potential benefits.

Here are some of the benefits that have been associated with DMAA, based on the available scientific literature.

Enhanced Physical Performance

DMAA has been found to enhance physical performance potentially.

It is often used in pre-workout supplements due to its stimulant-like effects.

It is believed to increase energy levels and improve focus, leading to more productive workouts.

A study published in the Journal of the International Society of Sports Nutrition found that a DMAA supplement improved both the time to exhaustion and the power output of the participants.

Weight Loss

DMAA has also been associated with weight loss.

It is often included in weight loss supplements due to its potential thermogenic effects.

Thermogenesis is the process by which the body burns calories to produce heat.

By increasing thermogenesis, DMAA could potentially help individuals burn more calories and lose weight.

A study published in the Journal of Dietary Supplements found that a multi-ingredient supplement containing DMAA led to significant weight loss in the participants.

Improved Mood and Focus

Some research suggests that DMAA may have nootropic effects, potentially improving cognitive function.

Users often report increased focus and improved mood after taking DMAA.

A study published in the Journal of Psychoactive Drugs found that a supplement containing DMAA improved the mood and focus of the participants.

Potential Risks and Considerations

While DMAA may offer certain benefits, it's important to note that it has been associated with potential risks and side effects.

Some users have reported experiencing increased heart rate, high blood pressure, and other cardiovascular issues after taking DMAA.

Furthermore, the U.S. Food and Drug Administration (FDA) has issued warnings about the use of DMAA, and it is banned in several countries.

As always, it's important to consult with a healthcare provider before starting any new supplement regimen.

Please note that while these benefits have been associated with DMAA in some studies, more research is needed to fully understand this compound's effects.

The studies referenced above were conducted with specific dosages and formulations of DMAA, and the effects may vary based on the dosage and individual factors.

The Risks and Side Effects of DMAA

While DMAA can provide several benefits, it has potential risks and side effects.

These can range from mild side effects such as headaches and jitteriness to more serious side effects such as high blood pressure, heart palpitations, and in rare cases, heart attacks.

It's also worth noting that the FDA considers DMAA an unsafe food additive.

Side Effects

Let's start with the side effects of DMAA...

Cardiovascular Issues

DMAA is known to increase heart rate and blood pressure, which can lead to various cardiovascular issues.

These can range from mild symptoms such as palpitations and shortness of breath to more serious conditions like heart attacks and strokes.

A study published in the Journal of Medical Case Reports documented a case of a 22-year-old man who suffered a heart attack after consuming a pre-workout supplement containing DMAA.

Neurological Effects

DMAA can also have a significant impact on the nervous system.

Users may experience symptoms such as jitteriness, nervousness, and dizziness.

In some cases, DMAA can even lead to seizures or cerebral hemorrhage.

A case report in the Journal of the Neurological Sciences described a young woman who developed a brain hemorrhage after taking a weight loss supplement containing DMAA.

Psychological Effects

The stimulant effects of DMAA can lead to a range of psychological side effects.

These can include feelings of anxiety, irritability, and mood swings.

In extreme cases, DMAA use can even lead to severe mental health issues such as psychosis.

A study in the Journal of Clinical Psychopharmacology reported a case of a man who developed acute psychosis after using a supplement containing DMAA.

You can learn more about the side effects, benefits and risks of DMAA here.


Here are some risks that come with DMAA...

Risk Of Overdose

Due to its potent stimulant effects, there is a significant risk of overdose associated with DMAA.

Overdose symptoms can include severe headaches, chest pain, difficulty breathing, and loss of consciousness.

In severe cases, a DMAA overdose can be fatal.

A case series in the Annals of Emergency Medicine reported several cases of severe illness and death associated with DMAA overdose.

Risk Of Dependency

Like other stimulant drugs, DMAA has the potential to be addictive.

Regular use can lead to tolerance, meaning higher doses are needed to achieve the same effects.

This can lead to physical dependence and withdrawal symptoms when the drug is discontinued.

A study in the Journal of Addiction Medicine documented cases of individuals who developed a dependency on DMAA.

Risk Of Interactions

DMAA can interact with several other substances, including other stimulants, medications, and alcohol.

These interactions can increase the risk of side effects and potentially lead to serious health complications.

For example, combining DMAA with caffeine can significantly increase the risk of cardiovascular issues.

A study in the Journal of Caffeine Research highlighted the potential dangers of this combination.

Safe Dosages Of DMAA

When it comes to the safe dosages of DMAA, it's important to note that the amount can vary depending on the individual's health status and tolerance.

However, some general guidelines can be followed based on the available studies.

According to a study published in the BMC Pharmacology and Toxicology, the typical dosage of DMAA in dietary supplements ranges from 25 to 75 mg.

They found that these dosages could increase blood pressure while not affecting the heart rate.

Another study published in the Journal of Human and Experimental Toxicology found that a single dose of 50 mg DMAA did not result in a statistically significant increase in blood pressure, heart rate, or body temperature.

However, they did note that there was a significant increase in energy expenditure.

research published in the Journal of Analytical Toxicology examined the effects of a pre-workout supplement containing DMAA (25 mg) and caffeine (250 mg).

They found that the supplement led to a significant increase in energy expenditure, but did not significantly affect heart rate or blood pressure.

It's important to note that while these dosages have been used in studies, the FDA has issued warnings about DMAA due to potential health risks, including high blood pressure and cardiovascular problems.

Therefore, it's crucial to consult with a healthcare provider before starting any supplement regimen that includes DMAA.

Remember, everyone's body reacts differently to supplements and what works for one person may not work for another.

Always start with the lowest possible dose to see how your body reacts and never exceed the recommended dosage on the product label.

Read more about the benefits, side effects and risks of DMAA.

Legal Status And Controversies Surrounding DMAA

The legal status of DMAA varies from country to country.

In the United States, the FDA has issued warnings about DMAA and has taken steps to remove dietary supplements containing the substance from the market.

However, some manufacturers continue to include DMAA in their products. Read more about the legality of DMAA here.

DMAA In Dietary Supplements

Despite the FDA's warnings, DMAA remains in some dietary supplements.

These supplements are often marketed as pre-workout boosters or weight loss aids.

While some users report positive effects from these supplements, the potential health risks make their use controversial.


What is DMAA?

DMAA, known as 1,3-dimethylamylamine, methylhexanamine, or geranium extract, is often found in pre-workout supplements and weight-loss products. It was originally developed as a nasal decongestant but has gained popularity in the fitness community for its perceived performance-enhancing effects.

Is DMAA safe to use?

DMAA is considered safe for healthy individuals when used at recommended dosages. However, it's important to note that the FDA advises consumers not to purchase or use DMAA products due to potential health risks, including increased blood pressure and cardiovascular problems.

What are the benefits of DMAA?

DMAA is known for its stimulant effects, which can increase energy, focus, and endurance. This makes it a popular ingredient in pre-workout supplements. However, these benefits should be weighed against the potential risks and side effects.

What are the side effects of DMAA?

Side effects of DMAA can include increased blood pressure, shortness of breath, tightening in the chest, and in severe cases, heart attack. Neurological and psychological conditions have also been reported.

Is DMAA legal?

The legal status of DMAA varies by country. In the United States, the FDA considers DMAA an unsafe food additive, and products containing DMAA are illegal to sell as dietary supplements.

Can DMAA be found in dietary supplements?

Yes, DMAA can be found in some dietary supplements, particularly those marketed for weight loss and performance enhancement. However, its presence is becoming less common due to safety concerns and legal restrictions.

What is the recommended dosage of DMAA?

Dosage recommendations for DMAA can vary, but studies suggest that doses of 90mg or less are generally safe for healthy individuals. However, it's always important to follow the specific dosage instructions on the product label and consult a healthcare provider if you have any concerns.

Can DMAA cause a positive drug test?

DMAA itself is not a banned substance in drug testing for employment or sports. However, because it's often found in combination with other ingredients in dietary supplements, it's possible that those other ingredients could trigger a positive result.

Can I take DMAA with other supplements?

It's important to be cautious when combining DMAA with other supplements, especially those that contain stimulants. Combining stimulants can increase the risk of adverse effects, including increased heart rate and blood pressure.

What should I do if I experience side effects from DMAA?

If you experience side effects from DMAA, stop using the product immediately and consult with a healthcare provider. In cases of severe symptoms like chest pain or shortness of breath, seek immediate medical attention.

Bottom Line

While DMAA can provide increased energy and focus, weighing these benefits against the potential risks is important.

The FDA advises against the use of DMAA due to potential cardiovascular risks.

However, studies show that DMAA is safe for healthy individuals at 90mg or less doses.

As with any supplement, it's important to consult a healthcare professional before starting any new supplement regimen.

by Nader Qudimat

Forged by iron and cold steel, I'm Nader, a mid-30s natural bodybuilder. Once a 100lb skinny guy, I've transformed into a 200lb muscular athlete with over 15 years of lifting experience. Today, I leverage my transformation and extensive experience to guide countless individuals on their fitness journeys.

Click here to check out my 12 year transformation: Natural 12 Year Transformation

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