By Nader Qudimat / Nov 15, 2017 DMHA GuideFrom DMAA to Ephedra and now DMHA (aka 2-Aminoisoheptane / Octodrine) ... Is this really the next best stimulant? Jump toPre Workouts Fat Burners DMHA Guide You want the strong stuff, don’t you?While the FDA may not want you to have DMAA, there’s another stimulant that is shaking the industry with lots of hype and promises.As soon as a popular stimulant like DMAA gets banned by the FDA, there is a rush to fill the void and, inevitably, some new variant comes onto the market that fits into the legal framework.Often, as time passes, that stimulant also gets banned, and the whole process starts over again.DMAA is still available but it may not be for long as the only supplier, Hi-Tech was raided recently, (10/07/17).As expected, the supplement industry has been scrambling for a replacement to DMAA.Enter DMHA.DMHA is claimed to be about 80% of the strength of DMAA.What is DMAA And Is it Legal?Methylhexanamine, commonly known as DMAA, is a stimulant that was first produced by Eli Lilly and Company in 1944 as a nasal decongestant.In 1983, that company withdrew it from the market.However, since 2006, it has been produced by supplement companies as a workout stimulant.Within a year many fat burning and pre-workout products were using DMAA as a key ingredient.It was often paired with caffeine, just as ephedrine had been.Mesomorph has DMAA along with caffeine. Check this out before it's completely gone from the market. The FDA didn’t take long to get interested in DMAA.In 2011, they came out and said that it is known to narrow the blood vessels and arteries which can elevate blood pressure and can lead to cardiovascular events ranging from shortness of breath to heart attack.In 2013, the FDA determined that DMAA was potentially dangerous and did not qualify as a legal dietary supplement.However, they did not ban the ingredient.Instead, they sent ‘warning letters’ out to the vast majority of supplement companies, but not all of them.Virtually every company got the message and removed DMAA from their products.One that didn’t was Hi-Tech Pharmaceuticals (more on them later).Hi-Tech's most popular DMAA and Ephedra based fat burner So now we have DMHA to “replace” DMAA’s role in hard hitting pre workouts.What is DMHA?With DMAA being pulled from the shelves, it was inevitable that that a schematically similar analog would emerge to take its place.That product is named DMHA (1,5 dimethylhexylamine) for marketing purposes.This name cleverly keeps it associated with, and easily confused with, DMAA.This new analog, DMHA, has an ambiguous claim to being consumed as a natural product that is consumed as a food source, which is required for it to pass the dietary Supplement Health And Education Act (DSHEA) guidelines of 1994.It is highly unlikely that any brand of DMHA currently on the market is selling an extract of the claimed source Aconitum kusnezoffii or related plants, because the root of those plants contains highly toxic alkaloids that have been attributed to severe, sometimes fatal poisoning (1).One research paper describes DMHA as being a component of the fruit of the plant Kigelia Africana, which is touted as being the definitive evidence that DMHA has been present in the food supply prior to DSHEA.The use of a chemically synthesized molecule weakens the argument against the likely stance to be taken by the U.S. Food and Drug Administration (FDA) that this is not a DSHEA-eligible natural product.The use of a synthesized chemical as opposed to an extract was one of the FDA’s points in declaring the related ingredient AMP Citrate also called DMBA, as an adulterant (3).Interestingly the marketers chose not to refer to DMHA by its former name, and the one commonly used in the few clinical papers that are available on this material - octodrine.Hydrazine is one of the strongest focus enhancing pre workouts out there and it's comparable to CrazeThough ‘DMHA’ has the benefit of the ‘DMAA’ phonetic association, it also avoids the uncomfortable realization (for those hoping to keep this product available as a dietary supplement) that octodrine was marketed as a drug (by such suppliers as Medley and James laboratories), which would invalidate its use as a dietary supplement based upon the FDA's prior actions and comments (4).Side EffectsSimilar to DMAA, octodrine was approved for and sold as a decongestant, and is noted for having vasoconstrictor properties.It is not readily found in products on the market at this time, and its current development appears to be directed toward its properties as an antifungal.The reason for octodrine’s absence in the marketplace as a decongestant is unknown, but presumably it was either less effective compared to comparable products or had similar side effects as DMAA when used as a nasal spray.These symptoms would be related to the effects of DMHA on the beta-1 adrenergic receptor, as well as being an alpha-2 adrenergic antagonist (similar to yohimbine).These may include elevated blood pressure, faster heart rate, shortness of breath, anxiety and other signs of distress (5).DMHA would appear to have innate risks for those with heart rhythm abnormalities and hypertension, and may have higher risks when combined with common stimulant ingredients such as caffeine, theobromine and theophylline.As a vasoconstrictor, DMHA would antagonize (or work against) vasodilators, ingredients which purport to enhance a pump by making the arteries feeding the exercised muscle open sider and make the muscle engorged like biceps on Viagra.Anecdotal reports are very enthusiastic about DMHA being everything DMAA should have been and more, with no comments about a performance decrement or loss of pump.Of course, these statements are primarily associated with websites that are selling DMAA-containing products, or affiliates.It is important to note that no human or animal studies have been published on the use or effectiveness of DMHA as a performance enhancer, stimulant of fat loss promoter.Those marketing DMHA are depending upon the structural similarities to proven compounds such as DMAA, DMBA and even the PEA-based products (6).Another potential side effect that may be associated with the use of DMHA that would be very disadvantageous to bodybuilders, especially those using anabolic steroids that are prone to gynecomastia, is its affinity with the estrogen receptor alpha and actions as an antagonist.This means that DMHA can stimulate estrogen-sensitive tissue just like estradiol, The female sex steroid.The concentration that this occurs as is the micromolar range, so the safe range of DMHA would be limited to the nanomolar range, which is a very small amount.This should not raise undue concern, as DMHA is not very potent as an estrogen receptor alpha agonist, but the effect does exist and has to be acknowledged.The chemical industry develops literature called ‘material safety data sheets’ of MSDS.The MSDS for octodrine (the same drug as DMHA) lists an acute oral toxicity, meaning that it is harmful if swallowed.The hazard classification suggests that it would take an unintentional act to induce self-harm acutely (i.e. All at once).As a category 4 hazard for oral exposure, this means that it would take over 300 milligrams per kilogram of bodyweight to approach the LD50 (’average’ lethal dose).However, this is when octodrine is taken as an isolated ingredient in a healthy person.Toss a few espresso, train in a dehydrated state with an undiagnosed cardiac dysrhythmia, and it may be good night permanently.The absence of any clinical trials on performance, body composition, food intake or resting energy expenditure makes it difficult to assess the potential benefits or effects of DMHA as a pre-workout, stimulant or fat-loss aid.Based upon the experiences seen with DMAA, which is structurally similar (with differences that may serve to DMHAs benefit, though again this is unproven - and only speculative from sources with interests in DMHA's market success promote this concept), those choosing to use DMHA products while they are available may see an enhancement in mood, energy or focus in regard to having more drive during a workout.Again, without and pharmacokinetic data, or data on its transport through the blood-brain barrier, this is based upon the speculation and reports of parties with a vested interest.One site does address that the degrading enzyme monoamine oxidase (MAO) would reduce the bioavailability of DMHA, and MAO is present in the gut.DMHA is unlikely to ever be sold as a solo ingredient, so it is impossible to tell how effective it may be compared to existing products or a couple hundred milligrams of caffeine.Whether any performance benefit can be claimed, or fat loss enhancement, is unproven.Until evidence arises that DMHA is safe, can remain on the market as a dietary ingredient and has documented proof of being an effective pre-workout stimulant or fat loss agent, it appears the prudent decision is to wait for further data.DMHA is the equivalent to being DMAA's chemical cousin.However, this is like a blind date.No matter how attractive your well-intentioned friend may be, his / her cousin may not get your blood pumping.Versions of DMHAThese include: Octodrine 2-Amino Isoheptane 2-Amino-6-methylheptane 1 5 DimethylhexylamineDespite these different names, there are actually only two versions of DMHA: 2-Amino-5-methylheptane 2-Amino-6-methylheptaneOf the two versions, 2 amino-5-methylheptane is the most potent.Octodrine, 2-Amino Isobutane and 1 5 Dimethylhexylamine are all based on the 2 amino-6-methylheptane version.The letters DMHA come from Dimethylhexylamine.DMHA DosageThe ideal dosage for best results in the gym appears to be between 100-150 mg of DMHA (the 2 amino-6-methylheptane version).This compares with a recommended dosage of 35-50 mg for DMAA. For the more powerful 2 amino-5-methylheptane, the recommended dosage is 75 mg.Kraken Extreme has 200mg of DMHA paired with 200mg caffeine and 150mg eria jarenesis, making it one of the most euphoric and energizing pre workouts of it's kind.DMHA vs AMP Citrate vs DMAAThere are a number of psychostimulants that share a very similar structure.They are all designed to make you more awake.These stimulants are: DMAA DMBA (AMP Citrate) Tuaminoheptane (2-aminoheptane) DMHABecause there have to date been no human or animal studies that quantify the specific actions of DMHA, the best we can, when trying to figure out how it works, is to take a look at the common features of these other products.From the get-go, you need to be aware that DMHA is an advanced stimulant that is designed for hardcore trainers who are looking to push the envelope.As mentioned, it does NOT have a ton of studies to back up what it can do.These psycho stimulants work by increasing the levels of key monoamines.Monoamines are neurotransmitters that contain a single amino group.The two monoamines that produce the most stimulant like effects to boost your performance are dopamine and norepinephrine.A compound will only work as a monoamine activator if it is structurally similar to monoamine itself.DMAA, and the other products that are structurally similar to it such as DMHA, have this structural similarity to dopamine and norepinephrine.This gives them the ability to release these two powerful neurotransmitters through the activation of trace amine associated receptor 1.At the same time, they are temporarily prevented from binding to target receptors.This allows dopamine and norepinephrine to remain active for longer, giving you a prolonged training effect. The Mental Benefits of DMHANot everyone who takes stimulants like DMHA are doing so for enhanced training effects in the gym.There are a lot of students and others who are more interested in their nootropic effects.They want to be able to study longer, be more focused and more productive in their studies.So how does DMHA stack up in this regard?User experience confirms that DMHA will ‘wake you up’ and allow you to focus more clearly on the task ahead.But there are benefits beyond that. It appears that the compounds that make up DMHA have the ability to improve memory.Specifically, they have the ability to increase episodic memory, which is your memory of past episodes.These are the types of memories that allow us to work out how we will respond to similar events in the future.As a result, DMHA will help you to work and study with more focus and to be better plan ahead.Dopamine, which DMHA works to enhance, is known to increase both the desire and the volition to do things.Volition is what gives you the ability to keep pushing on through obstacles and stumbling blocks.People who have more dopamine in their system are better able to persevere, work harder and stay on task.Dopamine also has the ability to affect the pleasure / reward center of the brain.It enhances our desire to repeat actions that lead to food feelings and our ability to remember the things that led up to the good feeling (7) (8).Thermogenic EffectsDMHA is also being used as in ingredient in fat burners.Its stimulatory nature gives it a thermogenic effect which speeds up the metabolism, leading to increased calorie burn.Clenadrol X by Ntel Pharma is one of the strongest DMHA based fat burners out there.Research / studies and what they foundFinding a stimulant that is able to activate monoamine release at a level that is not too strong nor too weak is difficult.DMAA was so popular – it did it at the ideal level of mildness, and so, apparently does DMHA.If the stimulant was too strong, it wouldn’t be able to be detached by the body’s enzymes.The next common features between DMAA and DMHA is the addition of a methyl group on the alpha carbon.This provides the following three effects:It limits the effects of monoamine oxidase (MAO). MAO is an enzyme which breaks down monoamines, so inhibiting it affects prolongs the half-life of the key monoamines dopamine and norepinephrine.It increases the ability of the monoamines to pass through the blood-brain barrier, increasing and enhancing their ability to improve your focus and energy levels.It increases the compound’s affinity for the catecholamine transporters; this decreases the reuptake of dopamine and norepinephrine. The more catecholamines that are available, the better the stimulant effect that is produced.DMHA is listed as a decongestant, which is precisely what DMAA was categorized by drug suppliers.2-amino-6-methylheptane was used as the key ingredient in a popular decongestant named Eskays Oralator back in the 1950’s.It appears to have fallen out of favour with the rise of ephedrine, which can still be used in medications, just not in supplements.So, why has 2-amino-6-methylheptane been classified as a decongestant.Let’s dig into the research to find the answer.During the 1940’s and ‘50’s there were a number of animal studies that are relevant.In 1952, a study was published in the British Journal of Pharmacology which found the following . . .The respirations of dogs under chloralose were stimulated by 2-amino-6-methylheptane and the stimulation lasted for sixty minutes.Chloralose is a sedative and anaesthetic used on animals.The focus of the above study was a group of compounds known as octylamines, one of which, 2-aminoheptane, is closely related to DMHA.The authors of this study concluded that 2-aminoheptane had an action that was similar to amphetamine, thought being less stimulatory and cardiovascular, less toxic and having a greater half-life.In 1947, a study was published in the Journal of Pharmacology and Experimental Therapeutics specifically focused on 2-amino-6-methylheptane, or DMHA.The following results were indicated: DMHA increased the pain threshold in cats, as a result of its anaesthetic and analgesic properties. DMHA is far less likely to increase blood pressure than epinephrine. However, it does still have a cardiac effect, increasing the heart-beat. When used intravenously in dogs, there was no effect on the small intestine, urinary bladder, urine secretion or respiration. Non-lethal 30-day large doses showed no damage to the heart, lung, liver, kidney, spleen, intestines, stomach, brain or spinal cords of the rabbits, rats and guinea pigs that were tested.The doses given were as follows: Rats – 20 mg/kg injected Rats – 75-100 mg/kg oral administration Guinea Pigs – 20-25 mg/kg injected Rabbits – 20 mg/kg injectedIt should be noted that the rats who took the high doses of 2-amino-6-methylheptane (both oral and injected) became depressed (9).The most important revelation to come out of the 1947 study was summed up in the following statement by study co-author Edwin Fellowes . . .While there is an indication of more activity after S-51 (DMHA) than absorbed in normal rats, a typical ‘amphetamine-like’ effect was never noted.In other words, rats that were given amphetamines were ‘literally’ banging their heads against the walls of their cages, whereas those who were given DMHA were hyped up, but not excessively so.The conclusion that we come to from an analysis of these animal studies from the middle of the 20th Century is that DMHA seems to possess the qualities that most people who are after a workout stimulant are after – it enhances your focus and output without making you hype (10), (11).DMHA EffectsThe general consensus among people who have used DMHA is that it works - really well!A lot of people felt that DMAA was just a little too over the top, producing a weird, unnatural buzz.But, DMHA provides you with about 80% of the effect of DMAA, which seems to be about perfect for gym applications.It is far more potent than other products that purport to be DMAA replacements, such as AMP Citrate.Users also report that DMHA provides you with a smoother ‘come-down’ than DMAA or even caffeine.You will not experience a crash, allowing you get on with the rest of your day without any after effects.For most people the effect of increased focus and energy lasted for several hours, providing you with greater productivity ability even after your workout is finished.DMHA vs CaffeineDMHA is a more potent stimulant milligram for milligram than caffeine.It will provide you with a greater energy level and that level of energy will be sustained for longer.DMHA’s other big benefit over caffeine is that it will not lead to a post workout energy crash.It also provides enhanced benefits as far as memory enhancement, due to the increased levels of dopamine that it contains.Possible Interactions with Prescription DrugsDMHA containing stimulants should NOT be mixed with prescription drugs.You should be especially careful not to mix DMHA with stimulatory prescription drugs, as well as antidepressants and MAO inhibitors.FDA And DMHAThe FDA has a very acute radar when it comes to stimulants.It doesn’t like them and has put in place stringent compliance requirements.The bottom line is that if it can be proven that the simulant occurs naturally in the environment, it is likely to meet compliance.It has been shown that 2-amino-5-methylheptane is found in nature - in walnut bark extract.The evidence for this is contained in a study entitled Evaluation of Antimicrobial Properties of Two Different Extracts of Juglans regia Tree Bark and Search for Their Compounds Using Gas Chromatography-Mass Spectrum (12).However, 2-amino-5-methylheptane is not DMHA (2-amino-6-methylheptane).It is, however, very similar.2-amino-5-methylheptane is reputedly more potent than DMHA. In order to meet FDA compliance, it needs to be shown that DMHA is derived from either: A vitamin A Mineral An herb or other botanical An amino acid A dietary substance used by humans to supplement the diet by increasing total dietary intake A concentrate, metabolite. constituent, extract or a combination of any of the aboveIn a 2014 study, the third of these compliance options was met.The study was entitled Metabolomic Profiling of Kigelia Africana Extracts with Anti-Cancer Activity by High Resolution Tandem Mass Spectroscopy.It identified that DMHA was present in the fruit Kigelia Africana.The study was published in a well-respected, peer reviewed academic publication that had absolutely no connections with the supplement industry (13).The discovery that DMHA occurs in a fruit boosts the possibility that DMHA will meet FDA compliance.There is another naturally occurring herb that may contain DMHA.It is the plant species aconitum, which is a flowering plant with over 250 species, found mainly in the Northern Hemisphere.Unfortunately, the aconite family are poisonous.This is clearly a massive red flag for the FDA.They are hardly likely to give compliance to DMHA if the natural herb or other botanical in which it is found is toxic.The question of compliance of DMHA by the FDA is an resolved one at this time.We expect that the pending court case Hi-Tech Pharma vs FDA will provide some further guidance on the issue (14).DMHA Banned in AustraliaAs of October 1st, 2017, DMHA was banned in Australia.At the same time DMBA will also come under ban.DMAA has been banned in Australia since 2013.It is interesting (and alarming) to note that the Australian Government’s Department of Health has not provided a single reason supporting their decision to ban DMHA.The Australian ban makes it illegal in that country to sell the following: Tim Muriello Spazmatic Sparta Nutrition Kraken OCD Nutrition OCD Extreme V2 Body War Pre War V2 All BPM products that contain Pouchong teaDrug TestsShould drug tested athletes take a stimulant that contains DMHA?The answer is NO, even though DMHA, under any of its names, does not currently appear on the WADA banned substances list.So why shouldn’t drug tested athletes take it?Because there is a very real possibility that DMHA in your system may cause a false positive result.This is all the more likely because of the structural similarity between DMHA and some other stimulants that ARE on the WADA banned substances list.Beyond this, WADA have a clause to include similar substances under their banned umbrella.Given that DMAA is on their list, DMHA would be included here as a similar product to DMAA.In addition, it is pretty likely that DMHA will actually be added to the banned list sometime soon.The bottom line here is that if you're a drug tested athlete, you should stay away from stimulants that contain DMHA.DMAA is still around / but not bannedThere is a lot of confusion surrounding the status of DMAA.Let's take a moment to clarify things.Between 2009 and 2012, DMAA was the key stimulant found in a number of powerful workout stimulants, including USP Jack3d and OxyELITE Pro.Then, in 2012, the FDA sent warning letters to the majority of supplement manufacturers, alerting them to the fact that DMAA was not a dietary supplement ingredient.Beyond this warning, however, the FDA did not state that DMAA was banned.The letter was sent to many companies but it was not received by Hi-Tech Pharmaceuticals, despite their having some of the best-selling DMAA containing products on the market.The majority of supplement manufacturers responded to the FDA warning letter by removing DMAA from their products.One company that did not do this was USP Labs, the manufacturers of Jack3d and OxyELITE Pro.The company actually sent a response letter to the FDA, claiming that DMAA was actually a naturally occurring compound, and therefore, passed compliance requirement under DSHEA 1994.In that letter, the USP Labs guy's cited three studies showing that DMAA was naturally occurring in the geranium plant and was, therefore, compliant with DSHEA 1994.The FDA responded to USP’s letter with several refutations.However, because their response is not publicly available, we do not know what these reasonings were.Around this time, USP Labs announced that it was no longer going to produce DMAA containing products.However, they cited business rather than legal reasons as the motivator for this decision.In November, 2013, US Marshals, at the behest the FDA raided the factories of Hi-Tech Pharmaceuticals.The Marshals seized more than two million dollars’ worth of DMAA based products. No warning letter was issued of this intention of seizure.In the wake of this action, Hi-Tech pharmaceuticals have taken the FDA to court.Their lawsuit is founded on the following grounds: They were not given any warning or opportunity to comply with any supposed regulations, leading to the loss of more than two million dollars’ worth of product. The FDA has never actually banned DMAA. A warning letter does not constitute a law. Therefore, there was no legal basis for the seizure of their products. DMAA is a legal, safe and natural product. For those reasons, it meets the compliance requirements of DSHEA 1994. Hi-Tech specifically claimed that DMAA is found in the geranium plant.While waiting for the lawsuit to come up in court, Hi-Tech set about developing new DMAA based stimulants, including HydroxyElite and Jack’d Up. In December, 2014, the FDA attempted to get Hi-Tech’s lawsuit thrown out of court.Three months later, the court denied the FDA request.At this point, we are still awaiting for the phase to come to court.In the meantime, the actual legal status of DMAA sits in the balance.It seems that, right now, Hi-Tech Pharmaceuticals is the only company selling DMAA containing products.All of the other companies have seen the writing on the wall and gone down the DMHA route.DMHA In NatureDMHA has been found to occur in nature.It is, according to a 2014 study, found in the plant Kigelia Africana.This is a tropical plant that grows in Northern and Southern Africa.It grows a fruit that can get up to two feet in length and looks somewhat like a sausage.The Kigelia Africana plant has well established anti-bacterial, anti-cancer and pain relieving properties.It also has a long history as a euphoria inducer.It therefore produces a natural stimulatory effect.There are sources that also state that DMHA is a component of the aconitum species of plant.This plant species, commonly known as aconite, comprises more than 250 different plants.However, aconite is one of the most poisonous plants that are out there.Two Versions of DMHA2-amino-5-methylheptane is one of the two versions of DMHA.It differs from 2-amino-6-methylheptane in that it has one less methylheptane.It is believed that 2-amino-5-methylheptane is the naturally occurring version of DMHA, whereas 2-amino-6-methylheptane is the synthetic version.2-amino-5-methylheptane is claimed to be more potent that 2-amino-6-methylheptane.As 2-amino-5-methylheptane is from a natural source, it is far more expensive to source than its synthetic version.Therefore, products that contain 2-amino-5-methylheptane will be very expensive.Dosing DMHADMHA is a powerful stimulant, even though it is only about 80% as potent as DMAA.You need to ensure, however, that you are not taking too much (or too little) of it.For that reason, you should never purchase a product that contains DMHA as part of a proprietary blend.Proprietary blends tell you what is in the product, but do not disclose the amount of each of those ingredients.In fact, we believe that all proprietary blends should be made illegal.Apart from the fact that proprietary blends force the consumer to guess at how much of each ingredient is in the product, they also attract the attention of the FDA.They are bad news all round and should be done away with.When you first start to use a stimulant that contains DMHA, we suggest that you take a half dose.Then assess how your body responds.Take your blood pressure and wear a heart rate monitor.If you don’t have hyper reactions, then slowly build up to a full dose.Game Day is contains DMHA but no artificial colors, appealing to the somewhat healthy market of pre workout consumers.The Future of DMHA (Octodrine)As mentioned at the outset, one of the many names that is given to DMHA is Octodrine.It is very interesting to note that Octodrine has been found (in two studies in 2015) to have antimicrobial and antifungal properties.One of the studies stated that . . .Was shown to be one of the most effective drugs in killing serum-grown Candida-albicans without significantly affecting the survival of host macrophages and skin cells.In another study, Octodrine was seen to kill e. Coli bacteria after five days of exposure.As we can see, then, Octodrine (or DMHA) has real potential to be used as a prescription antibacterial, anti-fungal yeast infection drug.This is a huge market potential that completely overshadows the fitness stimulant industry.If DMHA gets made into a prescription drug, it will automatically be banned as a supplement ingredient (15).Pre Workouts with DMHAIn establishing what other ingredients work best with DMHA we need to take a look at the most popular DMHA containing supplements on the market.These are: Tim Muriello Spazmatic Redcon 1 Total War Sparta Nutrition Kraken CT Fletcher’s Sidewalk KrakaThe common ingredients that these products pair with DMHA with are caffeine, Eria Jarensis, Higenamine and Hordenine.The average dosage of DMHA in these products is 100 mg per dose.These ingredients combine to provide a great blend of energy, focus, concentration and mood enhancement. Game Day by Man Sports Ingredients: DMHA Glycerol Monostearate GlycoCam (GPLC) PF5 Serum Protein Concentrate The ingredient list on the Game Day container does not disclose the individual ingredient dosages.Instead it lists two proprietary blends.The first one is called the Instant N.O. Stimulant blend for a total of 2635 mg.The second, which includes DMHA is called the IR Energy Blend for a total of 2298 mg.Game Day is a reformulated pre-workout from MEN'S Sports, which sits near the top of most pre workouts lists.It’s been around for long time and has established a reputation as powerful stimulant product that delivers plenty of energy, focus and pump effect.The latest version is even more powerful than the original formulation.Energy and FocusThis pre-workout takes a little more time to kick in than most, so you will want to take it about twenty minutes before you hit the gym.The energy level will build slowly over that twenty minute period.Soon you’ll have more energy than you need.Even though the energy provided is strong, it is not an unnatural intensity.The energy you get from this product is very smooth and natural.Game Day will provide you with a great deal of focus.It will clear your head, allowing you to get into the workout zone and stay in the zone all the way through your workout.That level of of alertness will also stay with you after your workout is over.You do get a decent level of pump with Game Day, but don’t expect that to be the major effect of taking this product.To enhance your pump effect stack Game Day with MEN's Pump Powder.As with any stimulant-based pre workout, there is somewhat of a post workout crash effect when you take Game Day.For that reason, you should be sure to not exceed one level scoop per serving.You can quickly build tolerance to this product, so should only be taken it twice per week. Use coupon code: FITFREK5 Check It Out Triple X By Gold Star Performance Products Ingredients: DMHA Agmatine Sulfate Beta-Alanine Arginine AKG Di-Creatine Malate DL-Malate, N-Acetyl-L-Tyrosine Methylxanthine Anhydrous The ingredient label of Triple X shows DMHA to be part of a proprietary blend of 7,316mg which includes L-Citrulline, DMHA, Agmatine Sulphate, Beta-Alanine, CReatine Monohydrate and Synephrine HCL.Triple X is a powerful pre-workout that combines a powerful blend of stimulants and includes creatine malate.It is designed to give an incredible pump and laser focus.The intense energy tapers off slowly, so that you don’t have to experience the crash that comes with other stimulant based pre-workouts.Triple X had very good mixability in a vortex, or shaker bottle.The kick-on factor is about twenty minutes, but when it dies, is given a super powerful effect.The beta alanine and agmatine sulphate combination in Triple X will provide an effective pump during your workout.Each bottle provides you with 30 servings. Use coupon code: SHARE12 Check It Out ReactR By Repp Sports Ingredients: Beta Alanine Betaine Anhydrous Taurine Citrulline Malate Acetyl L-Tyrosine Choline Bitartrate Mucuna Pruriens (98% L-Dopa) Caffeine Anhydrous DMHA (100mg) Caffeine Citrate Citrus Aurantium (30% Synephrine) Hordenine HCl Black Pepper Extract (95% Piperine) Yohimbine HCl ReactR delivers a 3-stage energy release formula to give you a sustained and focused energy surge throughout your whole workout.It delivers a potent timed release caffeine blend, an intensified pump and razor sharp mental focus.There is no crash associated with this product.The 100 mg of DMHA in this product is part of the Insane Energy Blend.This blend also includes two forms of caffeine - caffeine anhydrous and caffeine citrate, along with citrus arantium, which is also also known as bitter orange extract.There are seven ingredients in total in this blend for a total of 322 mg.ReactR is available in four unique flavors: Blue Magic Zap Berry Rainbow Burst Dragon Fruit Check It Out Re1gn by Olympus Labs Ingredients: L-Citrulline - 5g Agmatine Sulfate - 1g Pomegranate Powder Extract - 1g Caffeine Anhydrous - 300mg Eria Siamensis Extract Julgans Regia Extract Theacrine - 100mg RE1GN is a reboot of the extremely popular pre-workout from Olympus Labs - Conquer Unleashed.It contains J. Regia, also known as Persian Walnut or English walnut. J. Regia is a species of walnut tree indigenous to Southwest China and the Himalayas.More importantly, J. Regia is loaded with a number of alkaloids, which work to significantly enhance focus and energy.It is believed that J. Regia is extracted for 2-amino-5-methylheptane, which would make it a form of DMHA. J. Regia is slightly more powerful than other forms of DMHA, which means that you do not need as much of it.A major improvement over Conquer Unleashed is the taste and mixability.RE1GN not only provides you with a great energy kick, it also tastes great.The formulation consists of a three specific proprietary blends to target energy, focus and pump enhancement.Eria Jarensis has been added to provide a potent energy boost.The result is a smooth flow of energy and long term endurance, reduced fatigue and no post workout crash. Use coupon code: FITFREK5 Check It Out DVST8 Crimson by Inspired Nutraceuticals Ingredients: L-Citrulline - 8g Betaine Anhydrous - 4g Beta Alanine - 3.2g Taurine - 2g Raw Coconut Concentrate - 500mg Theobromine - 100 mg Hignemine - 40mg Caffeine - 325mg DMHA - undisclosed Yohimbine - undisclosed Synephrine - undisclosed DVST8 is a revamped version of what was already one of the top rated pre-workouts on the market.The addition of DMHA provides both a fat burning and an energy and focus boost to DVST8.You will get more pump, focus, energy and mood enhancement with this one.This product includes three different forms of caffeine within its 325 gram total.The addition of yohimbine and synephrine further enhance the endurance boosting effects of this product.Although the main focus of this product is a pre-workout energy enhancer, DVST8 is a better fast burner than many fat burners on the market.The unique combination of ingredients work to burn fat and suppress appetite.With this in mind, if you are trying to pack on mass, be sure to get in your post workout protein meal.Use coupon code: FITFREK5 Check It Out Excelsior by Imperial Nutrition Ingredients: Kigelia Africana Bauhinia Purpurea Hawthorn Extract Bitter Orange Extract Citrulline Betaine Excelsior is a powerful stimulant that provides you with long lasting energy, in connection with an enhanced pump effect.The focus here is on a proven effective plant based stimulants such as Kigelia Africana, which ramps up the central nervous system to boost energy levels.Bauhinia Purpurea adds a fat burning elements to the mix, while Hawthorn reduces MAO levels by 50%.This allows the stimulant effects of Excelsior to last a lot longer.Kigelia Africana is the base from which DMHA is extracted, providing a DMAA equivalent to provide a smooth energy and focus flow.Bitter orange extract contains a number of compounds that inhibit drug metabolizing enzymes in the body known as the CYP system.This also extends the life of this stimulant so you can train harder for longer.The effects of Excelsior will kick in within minutes of taking it, allowing you smash it from your first rep.This product also assists in advanced protein utilization and fat burning. Check It Out AREZ by NTel Pharma Ingredients: Beta Alanine - 3g Citrulline - 1g Arginine HCL - 1g Agmatine Sulfate - 500mg DMHA - 125mg Eria Jarenesis Extract - 75mg Synephrine HCL - 30mg Caffeine Anhydrous 350mg AREZ God of the Gym is a pre-workout that contains a total of 623 mg of powerful energy enhancing stimulants to rev up your workout.This includes 125 mg of DMHA to give you that tunnel vision and extras strength boost that you’re looking for.Eria Jarensis is added to give deliver a major cognitive enhancing effect by increasing the levels of dopamine and noradrenaline in your body.Beta alanine and citrulline add a strong pump effect, while 350 mg of caffeine anhydrous deliver a major stimulatory effect on the central nervous system, heart and muscles.The overall combination of ingredient mix is a very potent energy hit that comes on fast and lasts for around two hours.You do get a slight crash effect post workout that may have you wanting to take a nap.This product mixes well with a spoon or in a blender bottle and has a pleasant taste. Check It Out Preworkout by Iron Brothers Supplements (Most likely Discontinued or Reformulated Soon) Ingredients: L-Citrulline Beta Alanine Caffeine Taurine Yohimbine DMHA Caffeine Anhydrous Preworkout provides you with a powerful combination of stimulants to give you the energy boost that you want.Your energy levels will stay high without the full on crash that comes with other pre workouts on the market.There are also nitric oxide boosting ingredients here to deliver a strong pump effect.This is a reformulation of their previous pre-workout Relentless that provides more potency and a better taste than the original prodiuct.It has a very powerful energy boosting effect, so you will want to start with a half scoop to test out your body’s tolerance to the stimulants. Check It Out Enrage Extreme By eFlow Nutrition Ingredients: 350mg Caffeine 3.2g Beta Alanine 150mg DMHA Enrage Extreme is a potent stimulatory pre-workout that combines the proven energy boosting effects of caffeine with the powerful addition of DMHA, dosed at the upper range of the generally recommended range.You get a huge dosage of caffeine here, which will lead to such side effects as jitters and a noticeable post workout crash in most people.The amount of caffeine that you get with a single dosage is similar to taking 4 cups of coffee.You should start out with a half serving to assess your body’s tolerance level.This product also contains Eria Jarensis and Hordenie to provide focus and a fat burning effect.The product mixes well and has a pleasing taste. Check It Out Red White & Boom by Merica Labz Ingredients: L-Citrulline - 8g Creatine Monohydrate - 5g Beta Alanine - 3.2g Caffeine Anhydrous - 400mg DMHA - 150mg Synephrine HCL - 50mg Red, White and Boom provides a combination of stimulants and pump enhancers to provide all of the energy and blood flow that you need for an awesome workout.It pushes the boundaries on dosages, with 400 mg of caffeine and 150mg of DMHA, with the result that you will more than likely feel unnaturally wired and even a little bit jittery during the first 30 minutes that the stimulant effect kicks in.This product has an extremely sweet taste which may not be to everyone's liking.Reviewers have also reported that it doesn’t mix overly well, especially when using a shaker bottle.The product is probably a little oversized at one scoop, so start with half this amount and slowly work your way up if your body can handle it.Red, White and Boom is priced on the high side of the market. Check It Out Giant Rush by Giant Sports Ingredients: 185mg DMHA 40mg Bai Mudan White Tea (Camelia Sinensis) 300mg Caffeine 3g Citrulline 1.6g Beta Alanine 1g Taurine 1g Agmatine Sulfate Giant Rush is a simple, potent product that delivers a powerful energy kick.It is a clean and consistent form of energy, provides a thermogenic fat burning effect and a good amount of focus.The 185mg of DMHA is a slightly higher dosage than we see on many competing products (the standard seems to be 150mg), though, at 300 mg, caffeine content is down slightly.The taste of Giant Rush is not a strong point.However, you won’t get the jitters or crash effect on this product, unless, of course, you have an allergy to stimulants.What you will get is a clean, consistent and smooth energy rush, which is the whole of buying a pre-workout. Check It Out Hydrazine by Hydrapharm Ingredients: Bauhinia Purpurea Extract Cacao Extract Caffeine Anhydrous Cymbidium Goeringii Extract Kigelia Africana Extract Hydrazine provides a very potent ingredient mix that delivers a strong stimulatory effect.It also enhances your focus so that you can zoom in on your workout with laser like precision.The effect will kick in within minutes of taking it - and those effecst will last for at least a couple of hours.Hydrazine includes Bauhinia Purpurea Extract, which has been clinically proven to speed up cell regeneration and increase muscle building potential.It also includes the natural stimulant Cymbidium Goeringii Extract.DMHA is included through the kigelia africana extract, though we do not know what the dosage is.It will provide you with central nervous stimulation, focus and energy enhancement. Check It Out Spazmatic by Tim Muriello Ingredients: Caffeine - 400mg DMHA - 100mg Taurine- 2g Higenamine Hydrochloride - 30mg Tyrosine - 1g Spazmatic is a very powerful stimulant pre-workout that delivers a strong energy rush.It contains a very high dose of caffeine at 400 mg.This makes it quite likely that you will experience a crash effect and have jitters while you are training while on this product.The DMHA dosage is toned down to 100mg.There is no creatine or carnitine in this product.Their addition would have given a greater spectrum of strength enhancing and blood pumping benefits.Higenamine provides fat burning properties.You will want to start using this product cautiously.We suggest beginning with a half dose to assess how your body handles the huge dose of caffeine in each scoop.People who have an intolerance to stimulants should stay well away from Spazmatic. Check It Out RedCon1 Total War Ingredients: Citrulline Malate - 6g Beta Alanine - 3.2g Agmatine Sulfate - 1g Taurine - 1g Caffeine Anhydrous - 250mg DMHA - 100mg DICaffeine Malate - 100mg Higenamine HCL - 50mg RedCon1's Total War is designed to boost energy and focus, enhance blood flow for a greater pump effect and enhance strength and endurance.It contains a balanced mix of both stim and non-stimulatory ingredients.Unlike many of its competitors, Total War is not under dosed in Citrulline Malate.The 6 grams per serve will open the pathways for a serious pump, with the added benefit that you will delay the onset of training fatigue.Beta alanine is also well dosed at 3.2grams.It should be noted, though, that some people may experience a tingling sensation on the extremities and tongue from beta alanine at this dosage.The combination of caffeine at 250 mg and DMHA at 100 mg will provide you will solid stimulatory effect, without the jittery effects while training or the post workout crash that comes with higher dosages. Check It Out AREZ Black By NTel Pharma Ingredients: Beta Alanine - 3g Citrulline - 1g Arginine HCL - 1g Agmatine Sulfate - 500mg DMHA - 150mg Eria Siamensis Extract - 75mg Synephrine HCL - 30mg Caffeine Anhydrous 350mg Ephedra - 50mg Octopamine - 14mg AREZ Black is an enhanced version of AREZ that includes a blacklisted blend that includes 150 mg of DMAA, ephedra and octopamine.This combination provides a smooth energy boost that kicks in within about twenty minutes of taking it.You’ll experience greater energy for about two hours and then will come down gently without any post workout crash.You will also experience a significant boost to your cognitive functioning thanks to the synergistic effects of Eria Siamensis extract and synephrine HCL.Beta alanine and citrulline, at a combined dosage of 4 grams, will open up your blood vessels to deliver a strong pump effect during your workout. Check It Out Kraken by Sparta Nutrition Ingredients: Citrulline Malate - 4g Beta Alanine HydroMax Powdered Glycerol - 2g Taurine - 1g Agmatine Sulfate - 1g DMHA - 200mg Eria Jarensis Extract - 250mg Caffeine Anhydrous Kraken provides you with one of the highest dosages of DMHA that we have yet seen in a pre-workout stimulant at 200 mg per serve.This will boost your focus and energy while suppressing the appetite.Pairing this with 250 mg of Eria Jarensis extract to stimulate the central nervous system makes for a powerful synergistic combination.The combination of citrulline malate, beta alanine and hydromax to engorge the muscle with water delivers one of the most effective pump results that you will find in any pre-workout product currently on the market.Krakan will provide you with smooth, clean energy that is jitter free and that does not come with a dramatic post workout crash.The flavors all taste great and mix easily with nothing more than a glass and a spoon.Use coupon code: SHARE12 Check It Out DVST8 White Cut by Inspired Nutraceuticals Ingredients: L-Citrulline - 8g Betaine Anhydrous - 4g Beta Alanine - 3.2g Taurine - 2g Raw Coconut Concentrate - 500mg Theobromine - 100 mg Hignemine - 40mg Caffeine - 325mg DMHA - 200mg Yohimbine - undisclosed Synephrine - undisclosed DVST8 White Cut is an enhanced stimulatory version of the original DVST8 that delivers 200mg of DMHA to complement the 200mg of caffeine.This combination provides a huge improvement in your mental sharpness and focus, while also delivering a solid energy kick after about 15 minutes.The formulation includes electrolytes, raw coconut water and B Vitamins to help you get the best out of your training.All three flavors of DVST8 White Cut taste great and the powder mixes well with a spoon or in your shaker bottle.You won’t have to put up with the jittery effect that is common with other stim pre-workouts, but the beta alanine may cause a tingling sensation in your extremities.You should start with one scoop to allow your body to get used to this powerful product. Check It Out Sidewalk Kraka by CT Fletcher Ingredients: Beta Alanine - 3.2g Agmatine Sulfate - 1g Hydromax - 1g Choline Bitartrate 97% - 500mg Caffeine Anhydrous - 300mg DMHA - 125mg Eria Jarensis Extract - 200mg Therobromine 99% - 100mg CT Fletcher’s Sidewalk Kraka is a high potency stimulant pre-workout that pushes the envelope in terms of dosages.Fletcher markets himself as an outrageous, over the top sort of guy, and his product, naturally, carries on that trend.The stimulants (Caffeine, DMHA and Eria Jarensis Extract) combine to deliver 625mg of concentrated energy.This will definitely allow you to push through your workout at hyper speed, but it will also deliver a wired, unnatural jittery sensation, and will probably result in a substantial post workout crash.You should experiment with this before using it at the full dose.Start with a half dose just two or three times per week and monitor how your body responds for a while before taking it to the full extent. Check It Out Convict by Condemned Labz Ingredients: DMHA - 225mg Caffeine Anhydrous - 300mg Higenamine - 50mg L-Citrulline - 4g Beta Alanine - 2.5g Napopoot - 50mg Yohimbine HCL - 3mg L-Tyrosine - 500mg Convict is a super powerful stimulant based pre-workout that provides you with a serious energy jolt to power you through your workouts.At 225 mg, it contains the most DMHA that we have yet seen in any stim pre-workout product.On top of this you get 300mg of caffeine anhydrous which is, in itself, a high dosage.The combination of these two ingredients alone will get you hyper charged, both mentally and physically, for a great session.An ingredient that you don’t often see in a pre-workout is Noopept, which has recently developed a reputation as a very effective nootropic.It will get your focused and motivated.In addition the 6.5 gram combination of citrulline and beta-alanine will open up your blood vessels to allow for a sensational pump effect while you are training.This is a hardcore product that is designed for the serious, experienced trainer.We recommend starting with a half dose and working up from there.Begin taking Convict two to three times per week until your body gets used to it.You can expect to feel wired and jittery and to experience a post workout crash on this product. Check It Out Fat Burners with DMHA: Repp Sports by Raze Ingredients: Vitamin B6 - 10mg Vitamin B12 - 30mcg Caffeine Anhydrous DMHA Caffeine Citrate Cayenne Pepper Mucuna Pruriens Hordenine HCL Huperzine A Raze claim that Repp Sports is one of the most powerful fat burners on the market that is ephedra free.This claim is largely based on the inclusion of the two key stimulants, Caffeine anhydrous and DMHA.Unfortunately, they fail to disclose the actual ingredient dosages of these key compounds, choosing to hide them inside of a proprietary blend.As a result, we don’t know if they are clinically dosed or even sufficient to provide an apprecoable effect.The fat burning takes places through a three stage effect.Firstly, the compounds in this formula are designed to speed up your metabolism for enhanced calorie burning.It is also a potent thermogenic enhancer and delivers a strong focus and motivation effect to allow you to train harder and, therefore, burn off even more calories.This product is not designed for beginners.It is a potent stim fat burner that may be too much for many people to handle.You can expect a jittery effect with a post exercise energy come down. Check It Out EPH Bomb Fat Killer by GoldStar Ingredients: DMHA 250mg Caffeine circle B-Phenylethyamine HCl circle Nettle Root extract circle Snyephrine HCL circle Yohimbine HCl EPH Bomb Fat Killer by GoldStar is powered by DMHA, which it touts as the perfect replacement combination of DMAA and AMP Citrate.Unfortunately, GoldStar do not disclose just how much of this powerful ingredient they have put inside Infrared Thermogenic Fat Burner.Instead they have combined all of the ingredients (except for caffeine) into a proprietary blend of 245mg blend.We can assume that there will be about 100 mg of DMHA in there, but that is just a guess.The combination of ingredient will provide you with an energy enhancing boost that will act as an appetite suppressant while also delivering focused tunnel like training vision.You will not experience that crash effect that is common place with the vast majority of caffeine heavy stimulant pre workouts and fat burners on the market. Check It Out Synedrex by Metabolic Nutrition Ingredients: Caffeine Anhydrous Eria Jarensis DHMA Bitter Orange Extract Yohimbine HCL Hordenine Huperzine A Octopamine Synedrex contains all of the right ingredients, but, by hiding their individual dosages behind a 614 mg proprietary blend, Metabolic Nutrition has denied the end user the knowledge of how much of each ingredient he is actually putting into his body.This makes it difficult to ascertain just how effective a fat burner and energy booster this product will prove to be.In this latest version of Synedrex, DMAA has been replaced by DMHA and Eria Jarensis, which provide a similar, if slightly less intense, stimulant effect.AMP Citrate has also been removed in favor of the previously mentioned two ingredients, along with Yohimbe extract.You can expect a decent amount of fat burn, and user experience shows that there is no jittery effect or postexercise crash.From that we can speculate, you will be getting around 150mg of DMHA and something in the region of 200mg of caffeine with Synedrex. Check It Out VALKYRIE BURN by NTel Pharma (50mg) Ingredients: DMHA - 50mg Hoodia 200mcg T2 150mcg Biotin 600 mcg L-Carnitine HCL Conjugated Linoleic Acid (CLA) Caffeine Anhydrous Green Tea Extract Valkyrie Burn is a fat burner that has been specifically designed for the ladies.It provides a much lower dosage of DMHA than most other stimulant containing fat burner pre workout products.It contains 50 grams, which is substantially lower than what most experts are currently recommending.It also contains an undisclosed amount of caffeine anhydrous that works in conjunction with the DMHA to enhance energy, focus and central nervous stimulation.Hoodia is a Chinese herbal extract that works in harmony with the DMHA to produce an appetite suppressant effect. Check It Out Will Power by Iron Addicts Ingredients: DMHA - 100mg Eria Jarensis - 100mg Green Tea Extract - 500mg Choline Bitartrate - 500mg Caffeine Anhydrous - 250mg Teacrine - 50mg Vomitoria Extract - 2mg It is refreshing to come across a fat burning product that provides full disclosure on the ingredients label.With Will Power you know exactly what you're getting.At 100 mg, DMHA may be slightly under dosed.Yet, when teamed with Eria Jarensis and Caffeine Anhydrous (at 250 mg), it still delivers a pleasing, smooth energy supply.The increased stimulation boosts your metabolism.Choline Bitartate and Green Tea Extract provide extra cognitive benefits, while vomitoria extract contributes to fat metabolism and prevents fat storage.Tacrine has been added specifically to inhibit adenosine, which decreases feeling of fatigue. Check It Out KOR Lipolytic by Inspired Nutraceuticals (100mg) Ingredients: Higenamine Octopamine Cocoa Seed Theobromine Sulbutiamine Dicaffeine Malate Theacrine Synephrine DMHA - 100mg KOR Lipolytic is more of a middle of the range fat burner and a more intense nootropic, focus and energy enhancer.It contains a lot of cutting edge ingredients, that do a spectrum of things well.You will get a decent amount of fat loss, energy stimulation and motivation and focus.It is claimed that this product is a ‘lipolytic igniter’, turning your body into a fat burning furnace.The fat burning ingredients are not dosed highly enough to make this a spectacular fat burner, but it will allow you to get in a better, more focused and energetic workout.You will not get a post workout crash or experience any jittery effects when you take KOR Lipolytic. Check It Out Double Tap by RedCon1 Ingredients: Acetyl L-carnitine - 1g Green Tea Extract - 500mg Caffeine Anhydrous - 150mg Di-Caffeinate Malate - 150mg Teacrine - 100mg DMHA - 100mg Octopamine - 30mg Double Tap has been designed to increase your metabolic rate, increased body temperature, and decrease your appetite.You will also get a seriously high surge of energy to power you through your training.This is a very strong fat burner and stimulant, so you need to work your way up to full potency, which is 3 capsules twice per day.Start with half that amount and assess how your body reacts.The Acetyl L-Carnitine in this product has been added to start mobilizing body fat.There are two forms of caffeine, to provide a total of 300mg, which is relatively high. Tacrine has been added to enhance the effects of creatine.It amplifies the effect and keep the energy running smoothly through your entire workout.Octopamine increases body temperature so that you burn more calories throughout the day.DMHA is dosed at 100 mg here, which is a little lower than we normally see.However, it will act synergistically with the two caffeine's to provide an enhanced stimulatory effect. Check It Out Hydra Shred by Sparta Nutrition Ingredients: L-Carnitine - 2g Acetyl-L-carnitine - 500mg Garcinia Cambogia Extract - 250mg Eria Jarensis - 200mg DMHA - 150mg J. Regia Extract - 50mg Caffeine Anhydrous - 150mg Yerba Mate - 50mg Green Coffee Bean Extract - 50mg Decaffeinate Malate - 150mg Vanillin - 100 mg Hydra Shred is the latest fat burner out of the Sparta Nutrition stable.Contained within a dosage of four capsules are a large number of ingredients that are dosed at relatively low dosages.This helps to stave off the jittery, wired stimulant effect that is so common with many other stim based fat burners.The four capsules dose is spread over the course of the day, meaning that you get a constant supply of energy, focus and aft burn all day long.We do feel, however, that the majority of the ingredients in Hydra Shred are too low to be truly effective.However, DMHA is dosed here at what you find on most other stimulant products that are currently on the market.The overall result is a decent but not overly effective fat burner.You will actually get a greater stimulatory and nootropic effect from Hydra Shred. Check It Out Final WordsThe situation with DMHA is extremely fluid right now.If you haven’t yet tried it, we recommend that you do.If you have, and like what you have found, we suggest that you stock up on it.If history is anything to go by, DMHA will not be around for too much longer.It is possible that the Hi-Tech Pharma case will be decided in that company’s (and the industry’s) favor.Then again, the decision may go the other way.In addition, Big Pharma may get DMHA listed as a prescription drug, which would then make it unavailable as a supplement ingredient.The bottom line is to make the most of this supplement now while it IS available.References: Chan TY, Aconite Poisoning, Clin. Toxicol 2009:47; 279-285 Department of Health and Human Services (FDA). 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Being an ex-hardgainer, he has no choice but to keep training until he has surpassed in every way imaginable. You can follow Nader on Twitter (@DieselFitt).