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By Nader Qudimat / Nov 6, 2017

1-Testosterone by Hi-Tech Pharmaceuticals 

this powerful 1-andro based prohormone is made for bulking

1-Testosterone is a powerful anabolic stimulator that utilizes the only testosterone prohormone legally available on the U.S. market.

It has been shown to dramatically boost both muscle and strength in as little as four weeks.

Hi-Tech 1-Testosterone utilizes the Cyclosome delivery system to ensure maximum absorption.

It also includes 6,7 Dihydroxybergamottin for extended uptake.

This is one of the most powerful legal prohormones that we have encountered. 

Effectiveness

Based on a 2013 study, you can make incredible gains in both size and strength in just four weeks.

Ingredients

The ingredients included are going to increase absorption of the powerful 1-DHEA / 1-Andro here. 

Price

Price is fair for what you get and the gains that can be made. 

Availability

Hi Tech 1-Testosterone is readily available from a number of online supplement retailers.

We like

  • Super anabolic potency
  • Strength gain potential
  • Cyclosome delivery system
  • Addition of 6,7 Dihydroxybergamottin for prolonged effect

We Don't Like

  • 1-Testosterone is dosed a third less than in 2013 study
  • Kidney and liver impairing side effects

You're here to make gains and you're willing to go all the way right?

But you probably don't want to take steroids or anything of that extreme.

Luckily for you, you have a number of supplements to choose from and this one is 1-Testosterone by Hi-Tech Pharmaceuticals.

In 2014, the then President Obama outlawed the sale of prohormones in the United States. 

The reaction of those who were making millions off the sale of these chemical hormone precursors was to make adaptations to their products so that they passed the legal requirement.

Hi-Tech Pharmaceuticals is a company that makes products that push the boundaries.

They challenge the status quo and, more than often, bringing out products that are game changers. 

They strive to find a way to circumvent the regulations to produce products that are legal.

The first thing that the Hi-Tech Pharma guys did was to create a new delivery technology which allows for a much higher level of bioavailability, providing the prohormone at lower doses but with more effectiveness. 

Hi-Tech has gone all the way in formulating a very hardcore prohormone supplement... 

They then created a two-step conversion process to get to 1-testosterone, which is also known as 1-andro. 

Hi-Tech Pharma then set about creating a version of their prohormone that was going to meet the requirements of advanced, hardcore bodybuilders. 

These guys aren’t interested in minimal effects - they are after true steroid-like gains. 

What they came out with is 1-Testosterone and it is one of the hardcore 1-DHEA supplements out there today. 

Look at what's included...

  • 110 mg 1-Andro
  • Cyclosome Technology
  • Suitable for advanced bodybuilders who are bulking
  • Use on an 8-week off / four-week on cycle

Hi-Tech 1-Testosterone Ingredients

This product does not contain the hormone testosterone or it would be banned. 

Instead, it provides you with 1-Androstene, which converts into Testosterone through a two-step process that takes place in your body.

1-Androstene-3b-ol-17-one

1-Androstene-3b-ol-17-one is also known as 1-DHEA or 1-Andro. DHEA is a naturally occurring hormone in the human body.

As a result, it was not included among the banned substances under the 2014 legislation. 

1-Andro is a metabolite of DHEA.

1-Andro converts to testosterone through a two-step process.

Unlike many substances which are marketed to pack on muscle size, 1-Andro has some pretty solid scientific research to back up its effectiveness. 

How 1-Androstene-3b-ol-17-one Works

1-Andro basically allows you to build your own testosterone now that the raw product is illegal.

When you swallow 1-Androstene-3b-ol-17-one, it is sequentially converted by 3-hydroxysteroid dehydrogenase and 17-hydroxysteroid dehydrogenase enzymes to yield 17-hydroxy-5-androst-1-en-3-one, or, in other words, 1-testosterone.

Dosage: Is It Enough?

The only study that has ever been carried out on 1-Andro had subjects on a dose of 330 mg per day.

This resulted in an average gain of 8.8 pounds of lean muscle in just four weeks.

This was delivered as three daily doses of 110 mg.

However, the label recommendations on this product tell you to take a maximum of two 110 mg tablets per day.

This only provides you with two thirds the dosage of that were used in the study.

Of course, nothing stops you from using 3 tablets per day, but you will be going beyond the manufacturer's guidelines if you do.

It should be noted that this product benefits from Hi-Tech’s Cyclosome delivery system, which allows for better absorption.

This may make 2 tablets as effective as the three tablets used during the study.

What Can Andro-1 Do And Are There Side Effects?

The chemical structure of 1-Andro. ​Image courtesy of Wikipedia.

As mentioned, this product has been studied under legitimate scientific laboratory conditions.

The study was conducted out of Texas A&M University in 2013. 

Unlike many studies, the subjects were all trained athletes - 17 men between the ages of 18-35. 

They each took a dosage of 330 mg of Andro-1, spread out over 3 110 mg doses. 

They took the supplement for a total of 4 weeks. 

The results were outstanding. 

The overall level of muscle mass was increased, with the average lean mass going from 74 to 78.5 pounds. 

The increase in strength levels was even more impressive, with the average squat going from 365 to 405 pounds - remember that is in just 4 weeks!

In comparison, the placebo group lost weight, but added just a small amount of muscle.

The study did also record some side effects. 

There was an elevation in fatty acid levels as well as impaired liver and kidney functioning. 

However, the fatty acid levels returned back to normal once the subjects stopped using Andro-1.

The study subjects who were using Andro-1 also reported feelings of lethargy and a loss of libido.

On Cycle / Post Cycle Requirements

As indicated by the research, a cycling period will allow the user to control the side effects of increased fatty acid levels.

Cycling will also help to ensure that there is no conversion to estrogen.

The manufacturers of the product recommend an 8-week on, 4-week off cycle.

During your on cycle, it is recommended that you take a supplement like Ar1macare Pro by Olympus Labs, to help detoxify and improve the functioning of the kidneys and liver.

Ar1macare Pro has everything you need for your on-cycle care needs. Check it out here.

You may also want to consider taking a libido booster.

6,7 Dihydroxybergamottin (50mg)

6,7 Dihydroxybergamottin is a compound found in grapefruit extract.

It has been shown to break down the metabolism of steroids and other drugs.

This fruit contains a compound which prolongs the breakdown of certain steroids and drugs, which was also used in the study. 

This effectively allows the Andro-1 to stay in your system for longer which results in a greater anabolic effect and for a longer period of time.

This compound was used in the 2013 Texas A&M study at the same dose as used in 1-Testosterone.

Cyclosome Delivery System = phosphatidylcholine 75% / hydroxypropyl beta cyclodextrin (HPβCD).

Hi Tech Pharma’s Andro-1 goes a step beyond the compound that was used in the 2013 study by incorporating its patented Cyclosome Delivery System.

A lot of anabolic ingredients have a hard time being absorbed into the bloodstream by the small intestine. In fact, DHEA has just a 3-6% oral availability.

To overcome this problem, Cyclosome uses sugar and fats to bind to the compound in order to hugely boost its bioavailability.

The compounds used are cyclodextrin and liposomes.

Cyclodextrin (Starch Sugar)

Beta-Cyclodextrin is a large sugar molecule which forms a large ring around hard to absorb compounds like DHEA.

It therefore, encapsulates the hard to digest compound within its own very appealing form.

It’s a bit like hiding the vegetables inside a meat pie so that the kids will actually eat them!

There have been several studies to show the effectiveness of Cyclodextrin when it comes to boosting bioavailability.

A 1990 study showed that binding a protein with Cyclodextrin increased bioavailability by between 9 and 11 times.

Liposome For Increased Absorption

Liposomes are fats which have an equally impressive ability to encapsulate other compounds and increase their bioavailability.

In one study, liposomes were encapsulated with curculin, increasing its absorption by a staggering 29 times.

Studies have also been done to show how lipids specifically impact on the absorption of hormones (progesterone).

When paired with the lipids, the absorption of progesterone increased by a factor of 9. 

Dosage/ how to take/ off book approach 

We recommend that you go with the label directions, which are:

  • 2 capsules (each containing 110mg) daily, taken 12 hours apart
  • Take with food
  • Cycle off for four weeks after 8 weeks of continuous use
  • If you want to go off the book, increase to 3 capsules per day to match the 2013 study dosage

What To Stack With 1-Testosterone

We’ve already mentioned the wisdom of taking a cycle support supplement to help the liver and kidneys to do their job while you're on this product.

We recommend Ar1macare Pro by Olympus Labs, a very complete on cycle support supplement to cover all your needs.

Yes this on-cycle supplement is so good we had to show you twice!

You may also wish to take a libido enhancer during your cycle.

Be sure to keep your protein intake high, in order to provide the building material for lean muscle mass. 

Of course, it goes without saying that you have to be training intensely during your cycle as well.

Andro-1 should not be seen as a replacement to your standard pre and post workout supplements.

You should also be taking betaine, creatine, BCAAs, and such other amino acids as carnitine, glutamine and alanine.

Do I Need A PCT? (Post Cycle Supplement)

1-Testosterone is a powerful product.

Therefore, we recommend a post cycle therapy supplement (pct) like Sup3r PCT by Olympus Labs. 

This will allow your body’s natural testosterone production to normalize as quickly as possible.

You could also use either Nolvadex (tamoxifen citrate) or Clomid (clomiphene citrate).

Who Can Take 1-Testosterone?

The label on this product states a minimum age of 21.

However, we would suggest waiting a couple more years until your growth plates have fully fused.

This is a supplement designed for heavy duty, advanced bodybuilders (male or female).

You should be used to taking prohormones before jumping onto this stuff!

Should This Be Your First Prohormone?

No.

1-Testosterone is not designed to be used by first time prohormone users.

You shouldn’t even consider using a prohormone unless you have at least three years training under your belt.

You should also be at least 21 years of age.

Once you have established a solid foundation of training and nutrition (see the section below) and are supplementing with protein powders and pre-workouts as described in that section, then you may consider using a prohormone that has a high anabolic effect and a lower androgenic and estrogenic effect.

What To Take For Beginners

Your first prohormone should be a high anabolic product that has a minimal androgenic and estrogenic effect (aka minimal to no side effects).

They will produce fewer side effects, being more gentle on the liver and kidneys. It should include an over-the-counter cycle support product and have low toxicity. 

Unless you follow these guidelines, you will find that your estrogen levels will shoot up - and you’ll have mood swings.

Three great entry level prohormones are:

  • RPN Havoc
  • Competitive Edge Labs Cycle Assist
  • Fusion Supplements Arimistane

What Prohormones can be stacked with 1-testosterone?

We do not recommend stacking 1-testosterone with any other prohormones.

1-Andro and such other prohormones as 4-Andro make use of the same enzymes to make their conversions.

Taking both of these together will do nothing but saturate your body for no additional benefit.

The risk is too great for a big number of side effects. 

What's The Best Diet And Training While On Cycle?

Some key nutritional principles to follow:

  • Eat Frequently
  • Balance Your Macronutriets
  • Avoid Refined Carbs and Sugar
  • Drink Water

Let's take them one at a time....

Eat Frequently

The leanest, most muscular people on the planet all have one thing in common - they have abandoned the traditional 3 meals per day in favor of eating smaller, more frequent meals.

They have discovered that smaller, more frequent meals allow them to be harder, have more energy and stick to their clean eating plan.

Research backs them up.

A raft of studies indicate that if you feed your body balanced meals that contain quality protein and carbohydrates throughout the day - as many as six small meals spaced out every three hours - you’ll enjoy a number of spectacular benefits, including:

  • Enhanced metabolism.
  • Less stomach discomfort.
  • Stable energy levels throughout the day.
  • Controlled appetite.
  • It provides enhanced energy for your workouts.
  • It supports muscle growth.
Balance Your Macronutrients

Sensible eating requires taking in a healthy balance of macronutrients (protein, carbohydrate and fat).

Contrary to recent media reports, carbs are not your enemy. They are, in fact, your body’s preferred source of energy. You’ll need them to fuel your workouts.

Protein requirements for weight trainers are higher also.

Those who regularly engage in weight training exercise are routinely breaking down muscle tissue.

They need extra protein to repair all of this damage.

What’s more, they need it at specific intervals. In fact, timing of protein is very important.

We need it straight after a workout, about 30 hours later when muscle protein synthesis is at it’s highest - and even before bedtime to control cortisol levels and ensure that we’ve got a plentiful supply of amino acids coursing through our bloodstream while we’re sleeping.

To meet all of your body’s protein demands, aim for 1 gram of protein per pound of lean body weight.

Avoid Refined Carbs & Sugar

Here are a few general guidelines to follow while on cycle...

  • Concentrate on eating natural, unprocessed carbs.
  • Reduce processed refined carbs as much as possible.
  • Cut out white sugar and flour completely.
  • Include a mixture of both starchy carbs and fibrous carbs on your plate.
  • Eat fruit every day.
  • It supports muscle growth.

All in all, aim to take in 50% of your daily calories from carbs, with 30% coming from lean protein sources and 20% from healthy fats.

Drink Water

No one wants to be told to drink more water. It’s too easy - and cheap.

Everyone’s looking for some super supplement that will strip away the fat at lightning speed, allowing them to reveal a ripped, shredded, fat free body to startled onlookers.

To them there’s only one worthwhile piece of advice - Drink more water!

Without it nothing in your body works properly but with it, everything in your body works optimally.

If you ever find yourself dragging your way through a workout, it’s probably because you’re dehydrated.

When you lose just 5% of water weight, your strength level can drop by as much as 30% and thirst is not a good measure of hydration.

So carry a water bottle with you all the time, you'll eventually get used to it if you're not already.

Sip from it regularly - especially if you suddenly develop a between meal food craving.

Shoot for a gallon of water per day.

Protein: The Muscle Builder

Protein forms the structural material for every cell in your body.

Because your body can’t store protein, it needs to be supplied on a daily basis from the foods that you eat.

Amino acids are the building blocks of protein. 


Each protein contains between 50 and ninety thousand amino acids, all linked together.

Of the twenty different amino acids, 8 of them are not able to be manufactured by the body.

They are the essential amino acids and must be provided by the diet.

To properly make use of protein, all eight essential amino acids must be present in the body.

Essential amino acids come from animal sourced proteins, as well as soy products.

Plant proteins, such as beans, lentils and peanut butter, need to be combined to provide the full complement of essential amino acids.

To achieve this, you should combine grains and pulses, or grains and nuts.

For mass building purposes, it is recommended that you take in one gram of protein per pound of bodyweight.

For a 180-pound guy that would mean consuming 180 grams of protein per day.

That protein should be spread through the day, so if you are eating 6 small meals across the course of your day, you will be taking in about 30 grams of protein per meal.

The protein supplement market is a booming industry and because of this, many manufacturers make exorbitant claims about their products, usually in tandem with an image of some pro bodybuilder’s flexed bicep.

The following products are often listed on labels in their scientific guise to make them sound more impressive than they are.

Don’t be fooled - these are all relatively inexpensive and shouldn’t be sold at exorbitant prices:

  • calcium caseinate - milk protein
  • whey protein - a milk protein that is a byproduct of cheese manufacturing
  • lactalbumin - a specific whey protein
  • non-fat milk solids - skim milk powder
  • soy protein isolate - protein from soybeans
  • egg albumin - egg whites
  • dextrose - glucose
  • malto-dextrins - small chains of glucose molecules
  • xanthan, carrageenan, guar - vegetable gums often used as thickening agents​​​​
  • lecithin - an emulsifier that stops any fat from rising to the top of the drink

Whey protein is digested quickly, providing immediate muscle repair and growth materials for your muscle cells after a workout.

Soy protein is digested at an intermediate speed and casein protein is digested slowly.

That means that the whey and soy can work in tandem to assist in muscle synthesis straight after a workout, whereas casein provides an amino acid source a bit later.

Mixing the three proteins in one protein supplement blend is a smart way to minimize muscle breakdown while enhancing muscle synthesis in the hours after your workout.

Key Facts of Protein
  • Protein builds muscle
  • You need 1 gram per pound of body weight per day
  • You should have between 20-25 grams of protein at each of your 6 daily meals
  • A combination of whey (fast release), soy (medium release) and casein (slow release) protein is best for sustained muscle growth and repair.

Training for Size

In order to build a foundation of strength and muscle mass you need to perform heavy compound exercises.

These are the types of exercises that the old time bodybuilders like Arnold Schwarzenegger and Franco Columbu used to build their foundation.

Yet, too many guys today skip these foundational moves and jump directly to the glamor exercises like barbell curls.

Compound exercises are those that work a number of muscle groups together.

They allow you to perform functional moves involving a lot of weight.

These are the exercises that will allow you to build the clay that you can later shape with exercises like barbell curls.

The power exercises that you need to be doing during the first 6 months of your training career are:

  • Squats
  • Deadlifts
  • Bench Press
  • Bent Over Rows​​​​
  • Pull Ups

Best Exercises To Do While Bulking On 1-Testosterone 

Most beginning / intermediate bodybuilders overtrain.

They fall in love with the idea of getting big and strong and find themselves hitting the gym 5-6 times per week.

Then they wonder why they’re not growing.

One of the keys to building muscle is recovery. When you’re in the gym you are breaking the cell down.

It’s only when it is rested and fed that it grows back.

If you rest and feed it properly, it will grow back bigger than it was in the first place.

But, if you don’t give it enough time to recuperate, you will never build muscle.

You only need to be visiting the gym twice per week.

Give yourself at least three days between each session (i.e. Monday and Thursday).

In contrast to the way that most people are doing it, you should train your whole body in each session.

These are the exercises you need to be performing...

  • Squats
  • Pull Ups
  • Bench Press
  • Bent Over Rows
  • Deadlifts

Even though you’re only going to be doing 5 exercises, you will find this a very challenging workout.

Each of these compound exercises is very taxing, involving a large number of muscle groups.

These are moves that you will soon be able to build your weight considerably on.

Do five heavy sets of each exercise in the 5-8 rep range. 

Recommended Supplements:

Creatine

ATP is the fuel that powers your muscles.

When you are working out, ATP gets used up by being converted to ADP. When this happens, you lose strength and can no longer perform.

Creatine is a naturally occurring compound that has the ability to reconvert ADP back to ATP.

This allows you to extend your set, enabling you to push out more reps with heavier weight – and that makes all the difference in your muscle building endeavors.

Cor-Performance by Cellucor is a micronized form of creatine, allowing it to get into your bloodstream faster.

This 100% creatine product will boost your strength and endurance, providing 5 grams of creatine per serving.

Now you could simply take the cheapest creatine and still benefit from it.

So get something that fits your budget or use our top 10 list for creatine powders.

BCAA's

The Branch Chain Amino Acids (BCAA’s) are the amino acids L-Leucine, L-Isoleucine and L-Valine.

They are used more readily by the muscle tissue of your body than other amino acids.

Branch Chain Amino Acids are necessary post workout to get your body out of a catabolic state.

The branch chain amino acids are used by the body for energy when your glycogen stores are depleted instead of mu

This is a very simple but effective BCAA supplement that's worth looking into.

Optimum Nutrition's BCAAs provide anti catabolic (muscle wasting) and anabolic (muscle building) support to allow you to kick-start the synthesis of protein after your workout.

This product provides the scientifically preferred ratio of leucine to isoleucine and valine of 2:1:1.

But if you want more advanced BCAA supplements, check out our buying guide here.

The Best Protein Powder for Building Muscle and Losing Weight

Protein powders are not all created equal.

Many of them are packed with fillers and additives that will make you fat. 

100% Grass Fed Protein by Transparent Labs is one of the cleanest protein powders you can take...

Some also contain too many carbs in the way of maltodextrin and other sugars.

There are two most common categories of protein: whey and casein. 

Of the two, whey is the fastest to be absorbed by the body, making it the better choice during the day. 

However, the slow release of casein makes it the best option as a pre bedtime source of protein, allowing for a slow release of amino acids as you are sleeping.

Whey protein can be further divided into isolate, hydrolysate and concentrate.

They each have their benefits.

Isolate will provide the highest level of bioavailability, while hydrolysate is the fastest to be absorbed, and concentrate is the cheapest.

Supplement Side Effects

There are some common side effects from supplements that you need to be aware of, especially if you decide to use a prohormone such as 1-Testosterone. These are:

Dehydration - both caffeine and creatine are diuretics, meaning that they will lead to more frequent urination. Creatine will also draw water into your muscles cells, so you will want to drink more water when using creatine.

Kidney Problems - Too much creatine in your system can lead to the overproduction of such renal by-products as creatinine. This is bad news for your kidneys. For that reason, do not take more than 5 mg per day.

Elevated Blood Pressure - All stimulants will elevate your blood pressure. That’s because they operate by way of vasoconstriction, or the tightening of the blood vessels.

This makes it more difficult to pump the blood around your body, leading to elevated blood pressure.

Caffeine, DMAA, Bitter Orange and Guarana are especially likely to elevate your blood pressure.

The following supplements are known to lower blood pressure:

  • Ashwagandha
  • Cinnamon
  • Ginger
  • Flaxseed

Final Words

1-Testosterone from Hi-Tech Pharma is a serious muscle building anabolic supplement that contains the only Testosterone prohormone legally available on the U.S. market.

The inclusion of the Cyclosome delivery system ensures that you benefit from maximum absorption.

This is the strongest legal ingredient that we have come across.

How long it remains legal is anybody's guess.

So, if you can handle it, we suggest you get in quick - before it's no longer available.

Ready To Make Gains With 1-Testosterone?

1-Testosterone is one of the best prohormone supplements we've seen.

It not only contains the exact ingredients that was used in a groundbreaking study but it also takes advantage of Cyclodextrin which further enhances bioavailability of 1-DHEA. This prohormone is worth a try if you're in the market for something hardcore. 

As always, check with your doctor before trying anything like this. 

References:
http://jap.physiology.org/content/jap/116/5/560.full.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918227/
https://www.ncbi.nlm.nih.gov/pubmed/2146602

Forged by the iron and cold steel, Nader takes his knowledge and hulk smashes it into this puny site.

Being an ex-hardgainer, he has no choice but to keep training until he has surpassed in every way imaginable.

You can follow Nader on Twitter (@DieselFitt).

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