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Best Nitrosigine Supplements: Our Top 4 Picks

by Nader Qudimat
Updated July 24, 2023

If you're in the fitness world, you've probably heard of Nitrosigine.

It's a popular ingredient in pre-workout supplements, known for boosting nitric oxide levels and enhancing workout performance.

Nitrosigine Supplements: Our Top Picks

Nitrosigine supplements, such as N.O. XT by Jacked Factory and Pump Serum, are top choices for boosting nitric oxide levels, enhancing workout performance, and improving muscle pumps.

What is Nitrosigine?

Nitrosigine, scientifically known as inositol-stabilized arginine silicate, is a patented ingredient in many pre-workout supplements. It's designed to boost nitric oxide levels in the body, leading to better blood flow, increased muscle pumps, and improved nutrient delivery to muscles.

The Science Behind Nitrosigine

Nitrosigine works by boosting nitric oxide levels in the body. Nitric oxide is a molecule that plays a crucial role in many bodily functions, including:

  • Regulating blood pressure
  • Enhancing blood flow
  • Supporting immune and nervous system functions

Increasing nitric oxide levels leads to vasodilation or the widening of blood vessels. This improves blood flow and nutrient delivery to muscles, enhancing workout performance and recovery.

Several studies have shown the effectiveness of Nitrosigine. For instance, a study published in the Journal of the International Society of Sports Nutrition found that Nitrosigine significantly increased the body's arginine, nitric oxide, and silicon levels.

Benefits of Nitrosigine

The benefits of Nitrosigine are numerous and can significantly enhance your workout performance. Here are some of the key benefits:

  1. Enhanced Muscle Pumps: Nitrosigine helps increase muscle blood flow by boosting nitric oxide levels, leading to better nutrient delivery and waste removal. This results in enhanced muscle pumps, making your workouts more effective and satisfying.
  2. Increased Energy Levels: Nitrosigine has been shown to improve energy levels during workouts. This can help you push harder and longer, leading to better results.
  3. Improved Focus: Nitrosigine can also improve mental acuity and focus during workouts. This can help you stay dialed in and get the most out of your training sessions.
  4. Better Recovery: Nitrosigine can help improve recovery after workouts by enhancing blood flow and nutrient delivery. This means less muscle soreness and faster recovery times, so you can return to the gym sooner.

Adding Nitrosigine into Your Supplement Routine

Nitrosigine can be found in many pre-workout supplements, and incorporating it into your supplement routine can be as simple as taking a pre-workout supplement before your training sessions.

Below you will find the best Nitrosigine supplements you can choose from...

The Best Nitrosigine Supplements

When it comes to supplements that contain Nitrosigine, three products stand out: Pump Serum, Nitric Oxide by Jacked Factory, and Hydraulic by Axe and Sledge.

MEGA DOSED
Pump Serum by Huge Nutrition

Pump Serum v2 is the latest formula from Huge Nutrition, packing lots of citrulline, nitric oxide boosters and more. This is 30% off at the moment, use discount code FITFREK to get an extra 10% off.

Highlights:
  • Strong long lasting pumps
  • Nootropics included for focus
  • Optimizes performance and reduces fatigue
Ingredients: 8g Citrulline, 3g Betaine Anhydrous, 3g GlycerPump, 2g Beet Root Extract, 1.5g Tyrosine, 1.5g Nitrosigine, 1.25g Agmatine, 1g Pomegranate, 254mg VasoDrive, 980mg Choline Bitartrate, 157mg Himalayan Salt, 20mg Huperzine, 5mg Bioperine
Discount code: FITFREK
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Pump Serum by Huge Nutrition is a non-stimulant pre-workout supplement that stands out due to its comprehensive ingredient profile.

It's designed to enhance workout performance by promoting intense muscle pumps and improving endurance.

The formula includes a potent blend of ingredients: 8g Citrulline, 3g Betaine Anhydrous, 3g GlycerPump, 2g Beet Root Extract, 1.5g Tyrosine, 1.5g Nitrosigine, 1.25g Agmatine, 1g Pomegranate, 254mg VasoDrive, 980mg Choline Bitartrate, 157mg Himalayan Salt, 20mg Huperzine, and 5mg Bioperine.

Each of these components contributes to the overall effectiveness of the supplement.

Citrulline, for instance, is known for its ability to increase nitric oxide levels, which can enhance blood flow to the muscles during workouts. Nitrosigine, a patented complex of arginine and silicon, also boosts nitric oxide levels, further enhancing blood flow and nutrient delivery to muscles.

The inclusion of GlycerPump, a stable form of glycerol, helps improve hydration and endurance.

Pump Serum's comprehensive and potent formula positions it as a strong contender in the pre-workout supplement market.

If you want a more detailed analysis of its performance and effects, a full review is available here. Remember to use the discount code FITFREK for an additional discount.

AFFORDABLE
N.O. XT Nitric Oxide Booster by Jacked Factory

While N.O. XT isn't the most comprehensive nitric oxide booster, it is a budget pick, and it contains 3 good ingredients for pumps.

Highlights:
  • Contains multiple nitric oxide booster
  • Budget pick
  • Uses a potent antioxidant
Ingredients: 1.5g Citrulline, 500mg Nitrosigine, 200mg Glutathione, 5mg Bioperine
Discount code: FITFREK
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Priced at a budget-friendly $29.99, NO XT is one of the most affordable options on the market, including the powerful ingredient Nitrosigine.

NO XT isn't just about affordability, though. It's also about delivering a potent blend of ingredients to maximize your workout performance.

Each serving packs 1.5g of Citrulline, 500mg of Nitrosigine, 200mg of Glutathione, and 5mg of Bioperine.

This combination works synergistically to enhance muscle pumps, increase energy levels, and improve workout performance.

Nitrosigine, a patented complex of arginine and silicon, is particularly noteworthy.

It's been shown to significantly boost nitric oxide levels, enhancing blood flow, nutrient delivery, muscle pumps, and energy levels. So, if you're looking for a supplement that delivers value and performance, NO XT by Jacked Factory is a choice you won't regret.

You can snag an additional 10% off with the code FITFREK. Now that deal will have both your muscles and your wallet feeling pumped.

Vasomax V2 Pump Pre-Workout by Performax
Highlights:
  • Affordable pump supplement
  • Proper dosages of ingredients
  • Well rounded pumps
Ingredients: 6g 3DPump-Breakthrough, 2g Taurine, 1.5g Nitrosigine, 300mg Vaso6, 250mg Pink Himalayan Sea Salt, 200mg L-Glutathione, 50mg S7, 50mg AstraGin
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VasoMax by Performax, priced at $39.99, is a pre-workout supplement that offers a blend of ingredients designed to enhance muscle pumps, increase energy levels, and improve blood flow.

Each serving of VasoMax delivers 6g 3DPump-Breakthrough, 2g Taurine, 1.5g Nitrosigine, 300mg Vaso6, 250mg Pink Himalayan Sea Salt, 200mg L-Glutathione, 50mg S7, and 50mg AstraGin.

The combination of these ingredients is designed to maximize workout performance.

Nitrosigine, a patented complex of arginine and silicon, boosts nitric oxide levels, enhancing blood flow and nutrient delivery to muscles. 3DPump-Breakthrough and Vaso6 are unique ingredients designed to improve hydration and elasticity in the muscles and increase nitric oxide production, respectively.

With the discount code FITFREK, you can get an additional 10% off.

GREAT TASTING
Hydraulic Pump by Axe and Sledge

Hydraulic is a great tasting nitric oxide booster with a good foundation of ingredients for pumps.

Highlights:
  • Contains the basic nitric oxide boosters
  • Produces wet and dry pumps
Ingredients: 5g Citrulline, 3g GlycerPump, 2g Taurine, 2.4g Beta Alanine, 1.5g Magnesium Creatine Chelate, 1g Agmatine (AgmaMax), 1g Tyrosine, 1g Nitrosigine, 250mg N-Acetyl L-Tyrosine
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Hydraulic by Axe & Sledge is a stimulant-free pre-workout supplement designed to enhance muscle pumps and improve workout performance.

It offers a blend of ingredients that synergistically increase blood flow, enhance muscle nutrient delivery, and improve endurance.

The supplement contains 5g of Citrulline, 3g of GlycerPump, 2g of Taurine, 2.4g of Beta Alanine, 1.5g of Magnesium Creatine Chelate, 1g of Agmatine (AgmaMax), 1g of Tyrosine, 1g of Nitrosigine, and 250mg of N-Acetyl L-Tyrosine per serving.

Citrulline and Nitrosigine are known for their ability to increase nitric oxide levels, enhancing blood flow to the muscles during workouts.

GlycerPump, a stable form of glycerol, helps improve hydration and endurance.

Beta Alanine can delay muscle fatigue, allowing longer and more intense workouts.

Magnesium Creatine Chelate is a form of creatine known for its high bioavailability and effectiveness in increasing muscle strength and size.

Agmatine (AgmaMax) can enhance muscle pumps, while Tyrosine and N-Acetyl L-Tyrosine are amino acids that can improve focus and mood.

Hydraulic's comprehensive and potent formula makes it a strong contender in the pre-workout supplement market. It's designed to optimize your workouts, helping you push harder, last longer, and recover faster.

Comparing the Top Nitrosigine Supplements

While all three supplements - Pump Serum, Nitric Oxide by Jacked Factory, and Hydraulic by Axe and Sledge - contain Nitrosigine, they each have unique features and benefits.

Pump Serum stands out for its comprehensive formula that enhances pumps, improves focus, and reduces fatigue.

On the other hand, nitric Oxide by Jacked Factory is known for its potent nitric oxide boosting capabilities, thanks to the combination of Nitrosigine and L-Citrulline.

Hydraulic by Axe and Sledge differentiates itself by including Creatine MagnaPower and GlycerPump, which work together with Nitrosigine to deliver intense pumps and increased endurance.

Understanding Nitric Oxide Boosters

Nitric oxide boosters are supplements designed to increase nitric oxide levels in the body. Nitric oxide is a molecule that plays a crucial role in many bodily functions, including blood flow, muscle contraction, and nerve signaling.

The Science Behind Nitric Oxide Boosters

Nitric oxide boosters increase the levels of nitric oxide in the body. Nitric oxide is a molecule that plays a crucial role in many bodily functions, including blood flow, muscle contraction, and nerve signaling.

How Nitric Oxide Boosters Work

Nitric oxide boosters provide the body with ingredients to convert into nitric oxide. Here's a simple breakdown of how this process works:

  1. Intake of Nitric Oxide Ingredients: When you consume a nitric oxide booster, your body receives ingredients like Nitrosigine, L-Citrulline, Beet Root Powder, and Arginine.
  2. Conversion into Nitric Oxide: These ingredients are then converted into nitric oxide in the body. Various enzymes and biochemical reactions facilitate this process.
  3. Increased Nitric Oxide Levels: The increase in nitric oxide levels leads to vasodilation, or the widening of blood vessels. This enhances blood flow and oxygen delivery to muscles, leading to better performance and recovery.

The Benefits of Nitric Oxide Boosters

The benefits of nitric oxide boosters are numerous and can significantly enhance your workout performance. Here are some of the key benefits:

  1. Enhanced Muscle Pumps: Nitric oxide boosters increase muscle blood flow, leading to better nutrient delivery and waste removal. This results in enhanced muscle pumps, which can make your workouts more effective and satisfying.
  2. Increased Energy Levels: By improving blood flow, nitric oxide boosters can help increase energy levels during workouts. This can help you push harder and longer, leading to better results.
  3. Improved Recovery: Enhanced blood flow and nutrient delivery can also improve recovery after workouts. This means less muscle soreness and faster recovery times, so you can return to the gym sooner.
  4. Better Endurance: Nitric oxide boosters can help delay the onset of muscle fatigue, allowing you to train harder and longer.

Top Nitric Oxide Boosters

There are several nitric oxide boosters on the market, each with their unique features and benefits. Here are some of the top choices:

  • Nitrosigine: As we've discussed, Nitrosigine is a patented complex of arginine and silicon that boosts nitric oxide levels in the body. It's found in many pre-workout supplements and has been shown to enhance muscle pumps, increase energy levels, and improve focus.
  • L-Citrulline: L-Citrulline is an amino acid that boosts nitric oxide levels and helps delay the onset of muscle fatigue. It's been shown to improve strength and endurance, making it a valuable addition to any pre-workout supplement.
  • Beet Root Powder: Beet Root Powder is a natural source of nitrates, converted into nitric oxide in the body. This enhances blood flow and oxygen delivery to muscles, leading to better performance and recovery.
  • Agmatine: Agmatine, an endogenous metabolite of L-arginine, has been shown to boost nitric oxide levels significantly. It's a popular ingredient in many pre-workout supplements because it enhances blood flow and mood.

FAQ

What is Nitrosigine? Nitrosigine is a patented complex of arginine and silicon that has been shown to significantly boost nitric oxide levels, enhancing blood flow, nutrient delivery, muscle pumps, and energy levels.

What are the benefits of Nitrosigine supplements? Nitrosigine supplements can enhance workout performance and recovery by boosting nitric oxide levels, improving blood flow, increasing muscle pumps, and raising energy levels.

Are Nitrosigine supplements safe? Yes, Nitrosigine supplements are generally safe for most people. However, as with any supplement, it's always best to consult a healthcare professional before starting a new supplement regimen.

What are the top Nitrosigine supplements? The top Nitrosigine supplements include N.O. XT by Jacked Factory and Pump Serum. These supplements are highly rated for their effectiveness in boosting nitric oxide levels and enhancing workout performance.

How do Nitrosigine supplements work? Nitrosigine supplements provide the body with ingredients that can be converted into nitric oxide. This leads to enhanced blood flow, improved muscle pumps, and increased energy levels.

What is the difference between Nitrosigine and Citrulline? While both Nitrosigine and Citrulline can boost nitric oxide levels, Nitrosigine is a patented complex of arginine and silicon, while Citrulline is an amino acid. Both are effective, but they work in slightly different ways.

Can I take Nitrosigine supplements if I'm not working out? While Nitrosigine supplements are often used to enhance workout performance, they can also benefit overall health due to their ability to improve blood flow. However, it's always best to consult a healthcare professional before starting any new supplement regimen.

Are there any side effects of Nitrosigine supplements? Nitrosigine supplements are generally well-tolerated, but some people may experience side effects as with any supplement. These can include gastrointestinal discomfort, headaches, and changes in blood pressure. Always consult with a healthcare professional if you experience any adverse effects.

How long does it take for Nitrosigine supplements to work? The effects of Nitrosigine supplements can often be felt within 30 minutes to an hour of consumption. However, the exact timing can vary depending on individual factors such as metabolism and stomach contents.

Can I take Nitrosigine supplements with other pre-workout ingredients? Yes, Nitrosigine supplements can be taken with other pre-workout ingredients. In fact, many pre-workout supplements contain a blend of ingredients, including Nitrosigine, to enhance workout performance.

The Bottom Line

Nitrosigine is a powerful ingredient that can significantly enhance your workout performance. Boosting nitric oxide levels helps deliver better muscle pumps, increased energy, and improved focus. Whether you're a seasoned athlete or just starting on your fitness journey, Nitrosigine can be a valuable addition to your supplement routine.

by Nader Qudimat

Forged by iron and cold steel, I'm Nader, a mid-30s natural bodybuilder. Once a 100lb skinny guy, I've transformed into a 200lb muscular athlete with over 15 years of lifting experience. Today, I leverage my transformation and extensive experience to guide countless individuals on their fitness journeys.

Click here to check out my 12 year transformation: Natural 12 Year Transformation

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