SARMs Guide: Strongest Selective Androgen Receptor Modulators in 2019

By Nader Qudimat
Last Updated November 6, 2019
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BEST OVERALL

  • 3rd Party Tested
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SAFEST CHOICE

  • Increases muscle gains
  • Safer than LGD 4033 and Ostarine
  • Trustworthy company

Gains…

It’s hard to make them. 

You know this, everyone else does. 

If we could be Arnold Schwarzenegger's, then we wouldn’t be on Google searching about SARMs. 

When it comes to supplements, it’s easy to believe there’s the next best thing that could make all the difference in the world. 

But without the proof, research or reputation, the trend usually dies off and we continue looking for the next best thing. 

However, SARMs have been around at least 60 years and they don’t seem to be going anywhere anytime soon. 

These legal alternatives are touted to be the side effect free version of steroids, without the risks. 

Are they worth trying? Are there side effects?

First let’s start with… 

What are SARMs?

You may already know that SARMs are like steroids, but what they really are are selective androgen receptor modulators. 

They get a lot of attention in the medical community, though they have never been able to get medically approved. 

SARMs are suppose to increase physical performance, enhance appearance, and increase muscle mass without the common risks of steroids. 

They are believed to be safer than steroids, but they don’t have enough research to prove to be anywhere as powerful. 

Search for advice and places like Reddit will generally recommend spending the amount of money on steroids and get the most bang out of your buck, though that’s probably not the safest route for your health. 

SARMS vary and they include:

  • Ostarine (MK 2866 / GTx-024)
  • Andarine (S-4, GTx-007)
  • Ligandrol (LGD-4033, 3033)
  • Cardarine (GW-501516)

The more powerful a SARM is known to be, the lower starting dosage should be. 

How Do SARMs Work?

SARMs are very selective when it enters your body as they can work their way directly to muscles and bones. 

To understand how they work, you first should understand androgens. 

Androgens are the hormones that are produced by the male body, it’s what makes you have a deeper voice, hair growth, and muscle growth, etc. 

The body produces enough androgen to keep a balance in the hormones.

But when steroids are used, this balance is out of place and androgens are overly produced. 

This makes muscles grow faster, but it comes with side effects and risks like increased blood pressure, liver disease, heart dysfunction, aggression, baldness, breast development, etc. 

Anything that helps you make tremendous gains will always have great side effects. 

That’s where SARMs come in. 

They aren’t as powerful as steroids but they still help produce lean mass gains.

Not all SARMs were made safe. 

Some were left and abandoned for potential side effects.

On the other hand, some SARMs have made a reputation of being able to increase muscle growth without side effects. 

In fact, some SARMs are used as birth control pills for men. 

One of the first generation SARMs, LGD4033, was seen to have an effect on lean muscle gains. 

The problem is that research is still ongoing and it’s mainly used as an experimental way to increase muscle growth.

SARMs vs Prohormones

The main difference between SARMs and prohormones is that prohormones are illegal in the States and are classed as a Substance 3 controlled substance. 

SARMs are legal and though prohormones are powerful, there are very few that are actually worth the money.

Prohormones made waves around 2005, they were generally much more powerful back in the day. 

Being able to finding prohormones that work without harsh side effects is one challenge, but commonly the weaker ones still have side effects that make it unappealing to use. 

SARMs vs Steroids

Steroids requires strict supervision of a medical professional (i.e. doctor) and commonly they are used and abused, leading to addictive patterns that make it very dangerous choice for the common lifter. 

With SARMs they are much safer and although the strength is no where near anabolic steroids, they are safe to use generally. 

The only reason you should pick steroids over SARMs is if you are planning to compete against bodybuilders like Kai Greene. 

The risks are real with steroids and some of them are irreversible, making them not worth it. 

If you want to live a strong and long life, then you’ll always choose the safer alternative, and here it seems to be SARMs. 

How To Take SARMs

To understand how they work, you first should understand androgens.

Studies involving SARMs are very limited and is still ongoing.

All dosages recommended over the web are going to be anecdotal.

The good news is that there’s enough anecdotal evidence to suggest a starting point of 10mg.

The upper limit is around 30mg.

Some SARMs are more powerful than others, hence requiring the lower recommended dosage of 10mg.

When you start with 10mg, you can work your way up by 5mg per cycle of 6 weeks.

And SARMs can have different bioavailability, depending on the quality and processing used by the manufacture.

SARMs Legal Status

Since SARMs are a research chemical, they are not recommended for human consumption.

This means they are nor illegal or legal.

But when it comes to human consumption, they are illegal.

If you buy them, you can’t be arrested.

Worst case scenario, if you import them to your country, they may be confiscated if they are found by customs officers.

Strongest SARMs Available

Like steroids, SARMs are categorized by what they work best for.

Some work better for weight loss and cutting, others are known for muscle gains and strength.

That’s why it’s recommended to stack as they will produce favorable results if it’s done right.

Ostarine MK-2866

One of the two most popular SARMs, Ostarine, is known to maintain muscle mass, even under a calorie deficit.

It is widely used and it’s a popular choice when it comes to SARMs.

There’s a bit of research to back up Ostarine, check this out:

In a trial with 120 elderly people, a small dose of 3mg ostarine used daily for 12 weeks increased muscle mass and fitness.

It also increased insulin sensitivity and decreased blood glucose.

For bodybuilders, reports of 6-8lb of muscle gains were common but yet not anywhere comparable to what steroids would give.

Although the doses in studies were only 1-3mg daily, bodybuilders use ostarine at 10-25mg with a PCT being recommended due to the testosterone suppression that follows after a cycle.

These are what bodybuilders report when using ostarine:

  • Increase of muscle gains from 6-8lbs
  • No water retention
  • Increases strength and lifting endurance
  • No supplements required for organ support
  • Women report more obvious gains than men
  • Maintains muscle mass under strict diet conditions
  • No aggression

It seems too good to be true, but there are some reported side effects:

  • Testicle pain
  • Joint pain
  • Hunger increase
  • Nausea
  • Rare cases of gyno development
  • Low energy and depression
  • Testosterone suppression for up to 4 weeks without PCT use
  • Strength reduction

All of these benefits and side effects are reported and it may vary from person to person but most can agree that Ostarine can maintain muscle mass fairly well, making it perfect as a SARM to use for cutting and weight loss.

LGD 4033

If there’s one SARM that has quickly built a reputation of being the strongest and most effective, it’s LGD 4033.

It’s a fairly new SARM and it’s as popular, if not more popular than ostarine.

LGD 4033 is known to increase lean mass and strength while decreasing fat.

While there’s not enough research on this SARM, there are reports that suggest LGD 4033 to heal bone injuries and strengthen them.

Side effects have been reported in clinical trials but are very few and mild.

LGD 4033 has caught enough traction to be banned from professional sports, causing athletes to be banned if this SARM is detected in tests.

Dosages are anecdotal but it’s widely accepted to take LGD 4033 at 10mg per day, and keep it in mind it has a long half life of 24-36 hours.

Bodybuilders report:

  • Potent muscle gains (5-10lbs per month)
  • Increases fat loss
  • Enhanced recovery
  • Best for bulking
  • Protects muscle mass with low dosages of 5mg per day
  • Stacks well with cardarine for cutting and weight loss
  • May heal and strengthen bone
  • No risks on organs
  • No water retention
  • Comparable to testosterone
  • Strongest SARM for gains and overall physique development

Side effects are not confirmed by research but some users report:

  • Growth of breast tissue
  • Suppresses testosterone with high dosages (returns to normal after 4 weeks)
  • Post-cycle loss of gains were uncommon but reported

A lot of these can be prevented with a mild PCT but most agree that isn’t necessary.

LGD 4033 was developed with the goal of preventing muscle loss in the elderly and in those who suffer from muscle dystrophy.

Since it’s been seen to also increase and heal bone health, researchers are also looking into the potentail it may have for those suffering from osteoporosis.

There also seems to be some mental benefits as there are claims to increase cognition, energy and libido.

Testolone RAD140

RAD 140 is one of the newer SARMs introduced with very limited research.

But with an anabolic to androgenic ratio of 90:1, it seems to have a very promising potential.

Users, in theory, should experience massive anabolic effects and fast muscle growth without the usual androgenic side effects.

RAD140 seems to be more powerful than testosterone itself and dosing is very small, starting from 4mg going up to 12mg.

In comparison to Ostarine, it is very similar but it is supposed to be much more powerful.

Bodybuilders report:

  • Increases muscle mass
  • Reduces body fat
  • Improves cholesterol levels

Side effects are not confirmed by research but some users report:

  • Breast growth or tenderness in men
  • Male pattern baldness
  • Mood swings and depression
  • Increased body hair growth in women

RAD140 is known to be a safer alternative to testosterone replacement therapy but it can shut down the body's natural production of testosterone.

This may cause an increase in estrogen and a PCT would be required.

Since research is limited, side effects and safety is not fully understood.

A dose between 10 to 30mg is generally accepted throughout the bodybuilding community.

Ibutamoren MK-677

Ibutamoren, or MK-677, is a selective agonist of the growth hormone secretagogue receptor.

This sarm is different as it can act as ghrelin, the appetite hormone, which can increase growth hormone and IGF-1 without affecting cortisol levels.

MK-677 is usually taken before bed and for at least 3 months at a time for maximum effects.

Since it copies the action of the appetite hormone that regulates appetite, MK-677 can increase appetite. Whether this is a negative or positive will depend on your current diet and weight.

Ibutamoren doesn't seem to be worth trying as it seems to have dangerous side effects and some side effects may not be fully discovered yet.

If ibutamoren works as advertised then it would have these benefits. All of these benefits are associated with increased growth hormones.

Bodybuilders report:

  • Increase growth hormone levels and body mass
  • Reduces body fat
  • Decreases muscle loss
  • Increase bone density

Side effects are not confirmed by research but some users report:

  • Bad for cancer patients
  • May raise blood sugar
  • Increases risk for high blood pressure
  • Joint pain

Taking ibutamoren isn't recommended, one study was terminated due to adverse side effects.

Ending a study early is a big deal and all the reason to avoid taking the compound.

Other Strong SARMs Available:

Osta-Plex is Hi-Tech's answer to SARMs.

Hi-Tech is one of the few companies that brought phytochemical SARMs in the spotlight way back in 2008.

And this SARM that they made is Osthole, or 7-methoxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one.

This powerful legal SARM has a prohormone but it is a legal one, 19-nor DHEA.

This prohormone converts into one of three anabolic hormones, 19-norAndrestendione, 19-norAndrostenediol, and 19-NorTeststerone.

This chemical converts with one simple process, and research shows that it has potential for muscle growth without affecting androgens.

The SARM here has a structure that is remarkably similar to testosterone.

It has a effect that is similar to androgen and it can increase pumps.

To help with delivery, it includes Cyclosome.

PROS

  • Powerful, legal formula
  • Increases androgen and muscle mass without side effects
  • Increases nitric oxide levels

CONS

  • None

Andarine, or S4, is known to increase lean mass while forcing the body to use fat for energy.

Ostarine and LGD 4033 commonly have some side effects but Anderine is suppose to be the safer alternative to the two most powerful SARMs in the market.

Olympus Labs is known to have hardcore supplements, from their Test1fy, K1ngs Blood to their laxogenin supplements and SARMs.

Users report gains of about 3-4lbs with one cycle of Andar1ne and along with gains, motivation and energy are also seen with this SARM.

The main advantage is that it doesn't have any testosterone suppression nor does it need a PCT supplement.

PROS

  • No side effects
  • Increases muscle mass
  • Enhances motivation and energy

CONS

  • None

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