The reason why Annihilate is so strong is because it contains Laxogenin.
Laxogenin is a brassinosteroid, which is a plant hormone, and it's similar to animal steroid hormones in structure.
Compared to prohormones and SARMs, Laxogenin is safe to use but it's very anabolic.
It has the attention of bodybuilders because it has similar anabolic and androgenic as Anavar, although it's not as potent, Laxogenin still does not have any side effects.
In fact, Laxogenin is produced from the same plant steroid that's used as raw material for over 50% of synthetic steroids like testosterone, cortisone and progesterone. [1, 2]
But most supplements don't actually have Laxogenin, as 12 different supplements were analyzed and they were found to be contaminated with untested diosgenin. [3]
That's why Annihilate is our choice for Laxogenin as it comes from a trusted company that produce high quality supplements..
In one Russian study with rats performed long ago, they administered a brassinosteroid derivative similar to Laxogenin and found an increase in total weight and the protein content of the organs (liver, heart, kidneys) as well as the leg muscles were increased as well, without affecting the sex hormones or mimicking their effects. [4]
Another study used another plant brassinosteroid on rats and found they had increased their food intake, higher lean muscle mass, bigger leg muscles and increased physical fitness. They found with muscle cells, they had reduced protein breakdown and higher protein synthesis. [6, 7]
Researchers have also found a class of plant chemicals with a structure similar to brassinosteroids / phytoecdysteroids (check out our review on Ecdysterone here), had increased muscle growth and protein synthesis in muscle cells. [8, 9, 10, 11]
These compounds are similar to Laxogenin and belong to the same family of plant-based steroids with similar chemical structures.
And because there's a nice 100mg dose of Laxogenin in Annihilate, you'll sure to get more than enough to produce similar results to what the researchers have found in studies.
Annihilate has the potential to:
- Increase muscle protein synthesis
- Reduce body fat
- Prevent muscle breakdown
- Increase size and mass
- Reduce cortisol levels
Annihilate creates a very anabolic environment for the body to grow.
Since it may decrease cortisol levels, this will indirectly increase testosterone production.
Annihilate on it's own will help with gains tremendously, I can't imagine what it would be like to stack with something as potent as Ecdysterone.